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Peer-reviewedCC BY-NC-NDInternational Journal of Ophthalmology

Clinical outcomes of scleral lenses in keratoconus: a systematic review and Meta-analysis

  • Mojgan Pakbin1
  • Maryam Dashti1
  • Ali Reza Akbarzadeh Baghban2
  • Haleh Kangari1
  • Ali Ayatollahi1
  • Mohammad Ghassemi-Broumand1
  • Saeed Rahmani1
  1. 1Department of Optometry, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran 16169-13111, Iran
  2. 2Proteomics Research Center, Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran 19716-53313, Iran
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Abstract

AIM: To evaluate the efficacy and safety of scleral lenses (SLs) in patients with keratoconus. METHODS: Electronic databases including PubMed, Scopus, Web of Science, Embase, and Cochrane Library were systematically searched to find the articles on visual function and patient satisfaction following SLs fitting. A random-effects model was applied to specify the pooled values. RESULTS: Of 833 studies, 19 articles (704 eyes) and 14 studies (475 eyes) were included in qualitative and quantitative synthesis, respectively. Pooled mean difference (PMD) of best corrected visual acuity (BCVA) was -0.37 [95% confidence interval (CI), -0.48 to -0.26] logMAR in favor of SLs treatment. SLs markedly reduced ocular and corneal higher-order aberrations and increased the quality of vision. The overall pooled values for comfort, visual quality and patient satisfaction with SLs were 4.19 (95%CI, 3.83 to 4.55), 4.30 (95%CI, 3.97 to 4.64), and 80.83% (95%CI, 71.54% to 90.13%), respectively. The most reported complications were lens breakage (26.1%) and conjunctival injection (11.4%-15.8%). CONCLUSION: SLs fitting leads to improved visual outcomes and patient satisfaction in patients with keratoconus.

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Cite

BibTeXRIS
BibTeX
@article{pakbin2026clinical,
  title = {{Clinical outcomes of scleral lenses in keratoconus: a systematic review and Meta-analysis}},
  author = {Mojgan Pakbin and Maryam Dashti and Ali Reza Akbarzadeh Baghban and Haleh Kangari and Ali Ayatollahi and Mohammad Ghassemi-Broumand and Saeed Rahmani},
  journal = {International Journal of Ophthalmology},
  year = {2026},
  month = nov,
  doi = {10.18240/ijo.2026.11.17},
  url = {https://doi.org/10.18240/ijo.2026.11.17},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Clinical outcomes of scleral lenses in keratoconus: a systematic review and Meta-analysis
AU  - Mojgan Pakbin
AU  - Maryam Dashti
AU  - Ali Reza Akbarzadeh Baghban
AU  - Haleh Kangari
AU  - Ali Ayatollahi
AU  - Mohammad Ghassemi-Broumand
AU  - Saeed Rahmani
PY  - 2026
DA  - 2026/11/02
JO  - International Journal of Ophthalmology
DO  - 10.18240/ijo.2026.11.17
UR  - https://doi.org/10.18240/ijo.2026.11.17
AB  - AIM: To evaluate the efficacy and safety of scleral lenses (SLs) in patients with keratoconus. METHODS: Electronic databases including PubMed, Scopus, Web of Science, Embase, and Cochrane Library were systematically searched to find the articles on visual function and patient satisfaction following SLs fitting. A random-effects model was applied to specify the pooled values. RESULTS: Of 833 studies, 19 articles (704 eyes) and 14 studies (475 eyes) were included in qualitative and quantitative synthesis, respectively. Pooled mean difference (PMD) of best corrected visual acuity (BCVA) was -0.37 [95% confidence interval (CI), -0.48 to -0.26] logMAR in favor of SLs treatment. SLs markedly reduced ocular and corneal higher-order aberrations and increased the quality of vision. The overall pooled values for comfort, visual quality and patient satisfaction with SLs were 4.19 (95%CI, 3.83 to 4.55), 4.30 (95%CI, 3.97 to 4.64), and 80.83% (95%CI, 71.54% to 90.13%), respectively. The most reported complications were lens breakage (26.1%) and conjunctival injection (11.4%-15.8%). CONCLUSION: SLs fitting leads to improved visual outcomes and patient satisfaction in patients with keratoconus.
SN  - 2222-3959
SN  - 2227-4898
ER  -