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Peer-reviewedCC BY 4.0Clinical Case Reports

When the Antibiogram Offers Nothing Else: Ceftriaxone–Sulbactam–Disodium EDTA With Intravenous Colistin in Two Neonates With Metallo‐β‐Lactamase‐Producing Acinetobacter baumannii Meningitis

  • Naini Puri1
  • Shantanu Shubham1
  • Syed Moiz Ahmed1
  • Richa Joshi1
  • Divya Mishra2
  • Hanshmani Prasad Chaudhary3
  1. 1Department of Pediatrics Graphic Era Institute of Medical Sciences, Graphic Era Deemed To Be University Dehradun Uttarakhand India
  2. 2Department of Obstetrics and Gynaecology Graphic Era Institute of Medical Sciences, Graphic Era Deemed To Be University Dehradun Uttarakhand India
  3. 3Department of Pediatrics Nepal Medical College and Teaching Hospital Kathmandu Nepal
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Abstract

Two neonates with metallo‐β‐lactamase‐producing Acinetobacter baumannii meningitis, resistant to every tested alternative, received ceftriaxone–sulbactam–disodium EDTA plus intravenous colistin, which, to our knowledge, represents the first reported neonatal use of this combinations. Cultures were sterilized by day 7; both survived with normal assessments at 3‐months. Concomitant colistin precludes attributing the response to either agent.

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Cite

BibTeXRIS
BibTeX
@article{puri2026when,
  title = {{When the Antibiogram Offers Nothing Else: Ceftriaxone–Sulbactam–Disodium EDTA With Intravenous Colistin in Two Neonates With Metallo‐β‐Lactamase‐Producing Acinetobacter baumannii Meningitis}},
  author = {Naini Puri and Shantanu Shubham and Syed Moiz Ahmed and Richa Joshi and Divya Mishra and Hanshmani Prasad Chaudhary},
  journal = {Clinical Case Reports},
  year = {2026},
  month = nov,
  doi = {10.1002/ccr3.73664},
  url = {https://doi.org/10.1002/ccr3.73664},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - When the Antibiogram Offers Nothing Else: Ceftriaxone–Sulbactam–Disodium EDTA With Intravenous Colistin in Two Neonates With Metallo‐β‐Lactamase‐Producing Acinetobacter baumannii Meningitis
AU  - Naini Puri
AU  - Shantanu Shubham
AU  - Syed Moiz Ahmed
AU  - Richa Joshi
AU  - Divya Mishra
AU  - Hanshmani Prasad Chaudhary
PY  - 2026
DA  - 2026/11/05
JO  - Clinical Case Reports
DO  - 10.1002/ccr3.73664
UR  - https://doi.org/10.1002/ccr3.73664
AB  - Two neonates with metallo‐β‐lactamase‐producing Acinetobacter baumannii meningitis, resistant to every tested alternative, received ceftriaxone–sulbactam–disodium EDTA plus intravenous colistin, which, to our knowledge, represents the first reported neonatal use of this combinations. Cultures were sterilized by day 7; both survived with normal assessments at 3‐months. Concomitant colistin precludes attributing the response to either agent.
SN  - 2050-0904
ER  -