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Peer-reviewedCC BYCureus

Suspected Endomyocardial Fibrosis With Extensive Left Ventricular Thrombus: A Diagnostic Dilemma

  • Suria Mano Geran1
  • Safiyyah Burhani1
  • Shalu Sharma1
  • Aye T Hline1
  1. 1Cardiology, Queen's Hospital, Romford, GBR
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Abstract

We report a case of a 64-year-old man with biventricular dysfunction and a large left ventricular (LV) thrombus in whom endomyocardial fibrosis (EMF) was suspected. Despite extensive evaluation for eosinophilic, autoimmune, infective, and haematological causes, no secondary aetiology was identified. He was managed with guideline-directed heart failure therapy and anticoagulation. His condition progressively deteriorated, and he died within a year, highlighting the diagnostic challenge of suspected EMF when characteristic imaging findings coexist with atypical features and definitive histological confirmation cannot be obtained, as well as the therapeutic challenges of this rare cardiomyopathy.

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Cite

BibTeXRIS
BibTeX
@article{geran2026suspected,
  title = {{Suspected Endomyocardial Fibrosis With Extensive Left Ventricular Thrombus: A Diagnostic Dilemma}},
  author = {Suria Mano Geran and Safiyyah Burhani and Shalu Sharma and Aye T Hline},
  journal = {Cureus},
  year = {2026},
  month = nov,
  doi = {10.7759/cureus.119032},
  url = {https://europepmc.org/article/PMC/PMC13728760},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Suspected Endomyocardial Fibrosis With Extensive Left Ventricular Thrombus: A Diagnostic Dilemma
AU  - Suria Mano Geran
AU  - Safiyyah Burhani
AU  - Shalu Sharma
AU  - Aye T Hline
PY  - 2026
DA  - 2026/11/02
JO  - Cureus
DO  - 10.7759/cureus.119032
UR  - https://europepmc.org/article/PMC/PMC13728760
AB  - We report a case of a 64-year-old man with biventricular dysfunction and a large left ventricular (LV) thrombus in whom endomyocardial fibrosis (EMF) was suspected. Despite extensive evaluation for eosinophilic, autoimmune, infective, and haematological causes, no secondary aetiology was identified. He was managed with guideline-directed heart failure therapy and anticoagulation. His condition progressively deteriorated, and he died within a year, highlighting the diagnostic challenge of suspected EMF when characteristic imaging findings coexist with atypical features and definitive histological confirmation cannot be obtained, as well as the therapeutic challenges of this rare cardiomyopathy.
SN  - 2168-8184
ER  -