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Peer-reviewedCC BY-NC-NDInternal Medicine

Breakthrough Varicella

Abstract

A 27-year-old immunocompetent male presented with fever and rash.He visited our hospital on day 3 with papules that initially appeared on his face and spread painlessly to the trunk and extremities (Picture A, B).PCR testing for measles and rubella was negative.The lesions evolved into vesicles on day 5 (Picture C, D).Rapid antigen testing of a vesicular lesion on the anterior chest confirmed a varicellazoster virus infection.Because he had received a single varicella vaccination 19 years earlier, he was diagnosed with breakthrough varicella, which is defined as varicella in previously immunized individuals.Disseminated herpes zoster was considered unlikely because of the absence of derma-

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BibTeX
@article{furuya2026breakthrough,
  title = {{Breakthrough Varicella}},
  author = {Kento Furuya and Naoya Itoh},
  journal = {Internal Medicine},
  year = {2026},
  month = jul,
  doi = {10.2169/internalmedicine.7670-26},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7670-26/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Breakthrough Varicella
AU  - Kento Furuya
AU  - Naoya Itoh
PY  - 2026
DA  - 2026/07/11
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.7670-26
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7670-26/_article
AB  - A 27-year-old immunocompetent male presented with fever and rash.He visited our hospital on day 3 with papules that initially appeared on his face and spread painlessly to the trunk and extremities (Picture A, B).PCR testing for measles and rubella was negative.The lesions evolved into vesicles on day 5 (Picture C, D).Rapid antigen testing of a vesicular lesion on the anterior chest confirmed a varicellazoster virus infection.Because he had received a single varicella vaccination 19 years earlier, he was diagnosed with breakthrough varicella, which is defined as varicella in previously immunized individuals.Disseminated herpes zoster was considered unlikely because of the absence of derma-
SN  - 1349-7235
SN  - 0918-2918
ER  -