The chromatin-associated PWO proteins interface with circadian and epigenetic signaling to regulate flowering time in Arabidopsis
- 1University of Alberta
Abstract
Flowering time is a major determinant of reproductive success in plants and is regulated by several interconnected pathways which converge on few key flowering time-related genes. In the model plant Arabidopsis thaliana (Arabidopsis), both the circadian clock and chromatin-associated proteins integrate environmental cues to coordinate flowering (Staiger et al. 2013; Nohales and Kay, 2016; Du et al. 2019; Haider and Farrona, 2024). However, how the circadian-epigenetic signaling crosstalk regulates this crucial developmental transition has still been underexplored. PWWP-DOMAIN INTERACTORS OF POLYCOMBS 1 and 2 (PWO1 and PWO2) are chromatin-associated proteins that have been linked to the regulation of histone 2A (H2A) mono-ubiquitination (ub) (H2Aub) levels (Zheng et al. 2023). PWO1 and PWO2 also affect flowering time (Hohenstatt et al. 2018; Khan et al. 2026), but the underlying molecular mechanisms, their effects on clock genes, as well as their distinct contributions to flowering-time regulation remain mostly unknown.
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BibTeX
@misc{haider2026chromatinassociated,
title = {{The chromatin-associated PWO proteins interface with circadian and epigenetic signaling to regulate flowering time in Arabidopsis}},
author = {S. Haider and Q. Riviere and A. Shelton and A. Khan and A. A. Webb and I. Mozgova and S. Farrona},
howpublished = {bioRxiv},
year = {2026},
month = nov,
doi = {10.64898/2026.11.03.763775},
url = {https://www.biorxiv.org/content/10.64898/2026.11.03.763775v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - The chromatin-associated PWO proteins interface with circadian and epigenetic signaling to regulate flowering time in Arabidopsis
AU - S. Haider
AU - Q. Riviere
AU - A. Shelton
AU - A. Khan
AU - A. A. Webb
AU - I. Mozgova
AU - S. Farrona
PY - 2026
DA - 2026/11/03
PB - bioRxiv
DO - 10.64898/2026.11.03.763775
UR - https://www.biorxiv.org/content/10.64898/2026.11.03.763775v1
AB - Flowering time is a major determinant of reproductive success in plants and is regulated by several interconnected pathways which converge on few key flowering time-related genes. In the model plant Arabidopsis thaliana (Arabidopsis), both the circadian clock and chromatin-associated proteins integrate environmental cues to coordinate flowering (Staiger et al. 2013; Nohales and Kay, 2016; Du et al. 2019; Haider and Farrona, 2024). However, how the circadian-epigenetic signaling crosstalk regulates this crucial developmental transition has still been underexplored. PWWP-DOMAIN INTERACTORS OF POLYCOMBS 1 and 2 (PWO1 and PWO2) are chromatin-associated proteins that have been linked to the regulation of histone 2A (H2A) mono-ubiquitination (ub) (H2Aub) levels (Zheng et al. 2023). PWO1 and PWO2 also affect flowering time (Hohenstatt et al. 2018; Khan et al. 2026), but the underlying molecular mechanisms, their effects on clock genes, as well as their distinct contributions to flowering-time regulation remain mostly unknown.
ER -