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Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer

76 Tumor targeting and biodistribution of MK-4464, a CEACAM5-targeted NK cell engager, using [89Zr]MK-4464 PET in preclinical models and cancer patients

  • Konstantin Dobrenkov1
  • Danielle Vugts2
  • Mariette Labots3
  • Xiangjun Meng4
  • Marloes van Dongen5
  • Tapan Nayak6
  • Kerry A Riffel1
  • Daniel J Rubins1
  • Liza Gantert1
  • Ben Zwezerijnen7
  • Marc Huisman7
  • Wouter Vogel8
2 more authors
  • Amy Beebe1
  • C Willemien Menke-vander Houven van Oordt7
8 affiliations
  1. 1Merck & Co., Inc., Rahway, NJ, USA
  2. 2Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centres, Amsterdam, The Netherlands
  3. 32 Cancer Biology and Immunology, Cancer Centre Amsterdam, Amsterdam, Netherlands
  4. 4Shanghai Key Laboratory of Gut Microecology and Associated Major Diseases Research, Digestive Disease Research and Clinical Translation Center, Department of Gastroenterology, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
  5. 5Netherlands Cancer Institute, Amsterdam, Netherlands
  6. 6Merck, West Point, PA, USA
  7. 7Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, Netherlands
  8. 8Antoni van Leeuwenhoek Hospital, Amsterdam, Noord-Holland, Netherlands
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Cite

BibTeXRIS
BibTeX
@article{dobrenkov2026tumor,
  title = {{76 Tumor targeting and biodistribution of MK-4464, a CEACAM5-targeted NK cell engager, using [89Zr]MK-4464 PET in preclinical models and cancer patients}},
  author = {Konstantin Dobrenkov and Danielle Vugts and Mariette Labots and Xiangjun Meng and Marloes van Dongen and Tapan Nayak and Kerry A Riffel and Daniel J Rubins and Liza Gantert and Ben Zwezerijnen and Marc Huisman and Wouter Vogel and Amy Beebe and C Willemien Menke-vander Houven van Oordt},
  journal = {Journal for ImmunoTherapy of Cancer},
  year = {2026},
  month = nov,
  doi = {10.1136/jitc-2026-sitc2026.0076},
  url = {https://doi.org/10.1136/jitc-2026-sitc2026.0076},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - 76 Tumor targeting and biodistribution of MK-4464, a CEACAM5-targeted NK cell engager, using [89Zr]MK-4464 PET in preclinical models and cancer patients
AU  - Konstantin Dobrenkov
AU  - Danielle Vugts
AU  - Mariette Labots
AU  - Xiangjun Meng
AU  - Marloes van Dongen
AU  - Tapan Nayak
AU  - Kerry A Riffel
AU  - Daniel J Rubins
AU  - Liza Gantert
AU  - Ben Zwezerijnen
AU  - Marc Huisman
AU  - Wouter Vogel
AU  - Amy Beebe
AU  - C Willemien Menke-vander Houven van Oordt
PY  - 2026
DA  - 2026/11/04
JO  - Journal for ImmunoTherapy of Cancer
DO  - 10.1136/jitc-2026-sitc2026.0076
UR  - https://doi.org/10.1136/jitc-2026-sitc2026.0076
SN  - 2051-1426
ER  -