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Peer-reviewedCC BYDiscover Social Science and Health

An ecological analysis of legal policy environments and reported pre exposure prophylaxis availability for key populations in Asia Pacific countries

4 affiliations
  1. 1Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada
  2. 2Kartavya Disha Global Foundation
  3. 3Department of Public Health Dentistry, Goa Dental College
  4. 4Timori Kyomu Research and Innovation

Abstract

Objective This study aims to assess how national laws and policies affecting key populations relate to Pre-Exposure Prophylaxis (PrEP) availability across 40 Asia‑Pacific countries. We use a cross‑national ecological design and secondary UNAIDS data to quantify legal vulnerability and its association with PrEP programme presence and scale. Methods A quantitative ecological analysis was conducted using secondary data submitted by 40 Asia–Pacific countries to UNAIDS. Country-level indicators related to laws, legal protection rights, and participation of KPs in the development of HIV-related policies were extracted. Twenty-two indicators across four key populations—People Who inject Drugs (PWID: 7), female sex workers (FSWs: 4), transgender people (transgender people: 6), and men who have sex with men (MSM: 5)—were used to generate cumulative legal–policy scores for each country. Countries were categorised by reported PrEP availability (available, not available, or not reported). One-way analysis of variance (ANOVA) assessed differences in mean scores across groups, with Bonferroni post-hoc tests. Results Among the 40 countries, 12 reported PrEP availability, 14 reported non-availability, and 14 did not report PrEP status. Mean cumulative legal–policy scores (maximum = 22) were 8.92, 10.07, and 1.71, respectively. ANOVA showed statistically significant differences across groups, driven primarily by countries with non-reported PrEP data. Conclusions This ecological analysis suggests that non-reporting of PrEP and legal–policy indicators emerged as a structurally suggestive signal, pointing to possible links with unfavourable legal contexts and limited prevention readiness rather than neutral data gaps.

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BibTeX
@article{mali2026ecological,
  title = {{An ecological analysis of legal policy environments and reported pre exposure prophylaxis availability for key populations in Asia Pacific countries}},
  author = {Marcelo Amaral Mali and Abhishek Royal and Vaibhav Kumar and Atrey J. Pai Khot and Nelsensius Klau Fauk},
  journal = {Discover Social Science and Health},
  year = {2026},
  month = jul,
  doi = {10.1007/s44155-026-00459-7},
  url = {https://doi.org/10.1007/s44155-026-00459-7},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - An ecological analysis of legal policy environments and reported pre exposure prophylaxis availability for key populations in Asia Pacific countries
AU  - Marcelo Amaral Mali
AU  - Abhishek Royal
AU  - Vaibhav Kumar
AU  - Atrey J. Pai Khot
AU  - Nelsensius Klau Fauk
PY  - 2026
DA  - 2026/07/01
JO  - Discover Social Science and Health
DO  - 10.1007/s44155-026-00459-7
UR  - https://doi.org/10.1007/s44155-026-00459-7
AB  - Objective This study aims to assess how national laws and policies affecting key populations relate to Pre-Exposure Prophylaxis (PrEP) availability across 40 Asia‑Pacific countries. We use a cross‑national ecological design and secondary UNAIDS data to quantify legal vulnerability and its association with PrEP programme presence and scale. Methods A quantitative ecological analysis was conducted using secondary data submitted by 40 Asia–Pacific countries to UNAIDS. Country-level indicators related to laws, legal protection rights, and participation of KPs in the development of HIV-related policies were extracted. Twenty-two indicators across four key populations—People Who inject Drugs (PWID: 7), female sex workers (FSWs: 4), transgender people (transgender people: 6), and men who have sex with men (MSM: 5)—were used to generate cumulative legal–policy scores for each country. Countries were categorised by reported PrEP availability (available, not available, or not reported). One-way analysis of variance (ANOVA) assessed differences in mean scores across groups, with Bonferroni post-hoc tests. Results Among the 40 countries, 12 reported PrEP availability, 14 reported non-availability, and 14 did not report PrEP status. Mean cumulative legal–policy scores (maximum = 22) were 8.92, 10.07, and 1.71, respectively. ANOVA showed statistically significant differences across groups, driven primarily by countries with non-reported PrEP data. Conclusions This ecological analysis suggests that non-reporting of PrEP and legal–policy indicators emerged as a structurally suggestive signal, pointing to possible links with unfavourable legal contexts and limited prevention readiness rather than neutral data gaps.
SN  - 2731-0469
ER  -