Skip to content
DraconiticResearch
Search Sources API
203,952 studies31 sourcesUpdated 9 min ago
Peer-reviewedCC BY 4.0Advanced Science

Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures

  • Rui Zhang1,2,3
  • Tongfang Jing1,2,3
  • Leiming He1,2,3
  • Kaidi Cui1,2,3
  • Yuying Song1,2,3
  • Xuewei Mao1,2,3
  • Lidong Cao4
  • Lin Zhou1,2,3
4 affiliations
  1. 1College of Plant Protection Henan Agricultural University Zhengzhou Henan People's of Republic China
  2. 2Henan Key Laboratory of Creation and Application of New Pesticide Henan Agricultural University Zhengzhou Henan People's of Republic China
  3. 3State Key Laboratory of High‐Efficiency Production of Wheat‐Maize Double Cropping Zhengzhou Henan People's of Republic China
  4. 4Institute of Plant Protection Chinese Academy of Agricultural Sciences Beijing People's of Republic China
Read full textDOICite

Abstract

Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers. By modulating the mass ratio between tea polyphenols (TP) and non‐ionic surfactants, we generate fluid templates that are kinetically trapped via pH‐triggered iron complexation. This one‐pot protocol allows for the precise regulation of the micro‐to‐nano population ratio, effectively addressing the dimensional mismatch between soil retention and systemic uptake. The resulting architecture achieves a functional division: microcapsules function as stationary reservoirs for rhizosphere protection, while nanocapsules act as mobile vectors for systemic curative action. Furthermore, the metal‐phenolic shell exhibits pathogen‐responsive disassembly upon exposure to fungal virulence factors, including oxalic acid and cellulases secreted by Fusarium pathogens. Validated in a peanut root rot model, this system demonstrates improved spatiotemporal efficacy and reduced aquatic toxicity toward zebrafish compared to commercial formulations. Consequently, this work presents a versatile methodology for structuring dynamic liquid interfaces based on TP‐surfactant supramolecular interactions, offering a potent solution for precision agriculture through the controlled solidification of supramolecular assemblies.

Related

  1. Atom-precise nanocluster architectures programmed by biomolecular assembly
    Nandini Kundu, Eshana Bethur, Anna Gonzàlez-Rosell +4
    ChemRxivPreprintCC BY-NC-NDFull textMaterials & polymersChemRxiv
  2. TiO2–Carbon Nanotube Hybrid Gas Sensors: From Interfacial Mechanisms and Architectures to Performance Benchmarking and Design Rules
    Marciano Sánchez Tizapa, Miriam Tostado Plascencia, Alejandra Carreon-Alvarez +2
    Sensors (Basel, Switzerland)Peer-reviewedCC BYFull textEurope PMC
  3. Spatiotemporal Heterogeneity of HPV Integration Architectures Drive Oncogenic Features of Oropharyngeal Cancer
    W. Gu, A. D. Bhangale, X. Du +26
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  4. Interfacial chemistry of sulfide and halide solid electrolytes in all solid-state sodium batteries: from single electrolytes to functionally partitioned architectures
    Lin Li, Wenqian Tian, Siwu Li +3
    Chemical SciencePeer-reviewedCC BY 3.0Full textOrganic chemistryPMC
  5. Molecular‐Level Pore Engineering for Precise Separation via Active Solvent‐Mediated Interfacial Polymerization
    Feng Li, R. M. G. Rajapakse, Yuxin Mou +2
    Advanced SciencePeer-reviewedCC BY 4.0Full textHydrology & soilsPMC

Cite

BibTeXRIS
BibTeX
@article{zhang2026programmed,
  title = {{Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures}},
  author = {Rui Zhang and Tongfang Jing and Leiming He and Kaidi Cui and Yuying Song and Xuewei Mao and Lidong Cao and Lin Zhou},
  journal = {Advanced Science},
  year = {2026},
  month = aug,
  doi = {10.1002/advs.77149},
  url = {https://doi.org/10.1002/advs.77149},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures
AU  - Rui Zhang
AU  - Tongfang Jing
AU  - Leiming He
AU  - Kaidi Cui
AU  - Yuying Song
AU  - Xuewei Mao
AU  - Lidong Cao
AU  - Lin Zhou
PY  - 2026
DA  - 2026/08/11
JO  - Advanced Science
DO  - 10.1002/advs.77149
UR  - https://doi.org/10.1002/advs.77149
AB  - Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers. By modulating the mass ratio between tea polyphenols (TP) and non‐ionic surfactants, we generate fluid templates that are kinetically trapped via pH‐triggered iron complexation. This one‐pot protocol allows for the precise regulation of the micro‐to‐nano population ratio, effectively addressing the dimensional mismatch between soil retention and systemic uptake. The resulting architecture achieves a functional division: microcapsules function as stationary reservoirs for rhizosphere protection, while nanocapsules act as mobile vectors for systemic curative action. Furthermore, the metal‐phenolic shell exhibits pathogen‐responsive disassembly upon exposure to fungal virulence factors, including oxalic acid and cellulases secreted by Fusarium pathogens. Validated in a peanut root rot model, this system demonstrates improved spatiotemporal efficacy and reduced aquatic toxicity toward zebrafish compared to commercial formulations. Consequently, this work presents a versatile methodology for structuring dynamic liquid interfaces based on TP‐surfactant supramolecular interactions, offering a potent solution for precision agriculture through the controlled solidification of supramolecular assemblies.
SN  - 2198-3844
ER  -