Peer-reviewedCC BYActa obstetricia et gynecologica Scandinavica
The PCOS-to-PMOS shift in the broader history of nomenclature changes and its uncertain impact on clinical practice.
9 affiliations
- 1Institute of Genomics, University of Tartu, Tartu, Estonia.
- 2Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
- 3Department of Obstetrics, Gynecology and Gynecological Oncology, Medical University of Warsaw, Poland.
- 4Women's Health Research Institute, Calisia University, Kalisz, Poland.
- 5OVIklinika Infertility Center, Warsaw, Poland.
- 6Center for Fetal Medicine, Karolinska University Hospital, Stockholm, Sweden.
- 7Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
- 8Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
- 9Celvia CC AS, Tartu, Estonia.
Abstract
Proposed renaming of polycystic ovary syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS) aims to broaden multidisciplinary care. However, it may obscure reproductive manifestations and introduce phenotypic ascertainment bias. Historical examples of nomenclature changes suggest that clinical benefits depend heavily on diagnostic, therapeutic, and etiological advances and education. Although formal cost-effectiveness analysis of nomenclature changes are lacking, our preliminary estimates suggest that implementation may entail substantial cost and healthcare resource requirements, while its clinical benefits remain uncertain.
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BibTeX
@article{aleksejevazagura2026pcostopmos,
title = {{The PCOS-to-PMOS shift in the broader history of nomenclature changes and its uncertain impact on clinical practice.}},
author = {Elina Aleksejeva-Zagura and Piotr Laudański and Ganesh Acharya and Andres Salumets},
journal = {Acta obstetricia et gynecologica Scandinavica},
year = {2026},
month = oct,
doi = {10.1111/aogs.70380},
url = {https://europepmc.org/article/MED/42952411},
note = {CC BY},
}
RIS
TY - JOUR
TI - The PCOS-to-PMOS shift in the broader history of nomenclature changes and its uncertain impact on clinical practice.
AU - Elina Aleksejeva-Zagura
AU - Piotr Laudański
AU - Ganesh Acharya
AU - Andres Salumets
PY - 2026
DA - 2026/10/29
JO - Acta obstetricia et gynecologica Scandinavica
DO - 10.1111/aogs.70380
UR - https://europepmc.org/article/MED/42952411
AB - Proposed renaming of polycystic ovary syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS) aims to broaden multidisciplinary care. However, it may obscure reproductive manifestations and introduce phenotypic ascertainment bias. Historical examples of nomenclature changes suggest that clinical benefits depend heavily on diagnostic, therapeutic, and etiological advances and education. Although formal cost-effectiveness analysis of nomenclature changes are lacking, our preliminary estimates suggest that implementation may entail substantial cost and healthcare resource requirements, while its clinical benefits remain uncertain.
SN - 0001-6349
SN - 1600-0412
ER -