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PreprintCC BY-NC-NDChemRxiv

Stereospecific Conversion of Alkenyl and Epoxy Carbamates into Cyclic Carbonate Alcohols

  • Raju Silver1,2
  • Dnyaneshwar A. Gorve1,2
  • Steven P. Kelley3,4
  • Shyam Sathyamoorthi1,2
4 affiliations
  1. 1Department of Medicinal Chemistry
  2. 2University of Kansas
  3. 3Department of Chemistry
  4. 4University of Missouri—Columbia
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Abstract

We have thoroughly explored the conversion of alkenyl and epoxy carbamates into cyclic carbonate alcohols. The substrate scope is robust, and the products are amenable to further transformations. In almost all cases, the reactions are predictably regioselective and stereospecific. The reactions can be run open to air and without precautions to exclude moisture. Indeed, H2O plays a critical role in the transformations and is added to the reactions as a key reagent.

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Cite

BibTeXRIS
BibTeX
@misc{silver2026stereospecific,
  title = {{Stereospecific Conversion of Alkenyl and Epoxy Carbamates into Cyclic Carbonate Alcohols}},
  author = {Raju Silver and Dnyaneshwar A. Gorve and Steven P. Kelley and Shyam Sathyamoorthi},
  howpublished = {ChemRxiv},
  year = {2026},
  month = oct,
  doi = {10.26434/chemrxiv.15010491/v1},
  url = {https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010491/v1},
  note = {CC BY-NC-ND},
}
RIS
TY  - UNPB
TI  - Stereospecific Conversion of Alkenyl and Epoxy Carbamates into Cyclic Carbonate Alcohols
AU  - Raju Silver
AU  - Dnyaneshwar A. Gorve
AU  - Steven P. Kelley
AU  - Shyam Sathyamoorthi
PY  - 2026
DA  - 2026/10/15
PB  - ChemRxiv
DO  - 10.26434/chemrxiv.15010491/v1
UR  - https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010491/v1
AB  - We have thoroughly explored the conversion of alkenyl and epoxy carbamates into cyclic carbonate alcohols. The substrate scope is robust, and the products are amenable to further transformations. In almost all cases, the reactions are predictably regioselective and stereospecific. The reactions can be run open to air and without precautions to exclude moisture. Indeed, H2O plays a critical role in the transformations and is added to the reactions as a key reagent.
ER  -