Peer-reviewedCC BYAnnals of medicine and surgery (2012)13 Oct 2026

Efficacy and safety of low-dose triple and quadruple combination pills for initial hypertension management: a systematic review and meta-analysis of RCTs

Asad Ali Ahmed Cheema¹
Syed Moiz Abbas²
Laiba Nadeem³
Hafsa Azam²
Ahmed Muneeb Rashid⁴
Khadija Alam⁵
Kumail Mustafa Ali²
Abdur Rafay Bilal⁶
Muzamil Hamid Hussain⁷
Chaudhry Saad Sohail⁷
Syed Sarmad Javaid⁸

8 affiliations

¹Department of Medicine, International School of Medicine, International University of Kyrgyzstan, Bishkek, Kyrgyzstan
²Department of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan
³Department of Medicine, Karachi Medical and Dental College, Karachi, Pakistan
⁴Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
⁵Department of Medicine, Liaquat National Hospital and Medical College, Karachi, Pakistan
⁶Department of Medicine, Ziauddin Medical College, Karachi, Pakistan
⁷Department of Internal Medicine, University of Mississippi Medical Center, Jackson, United States
⁸Department of Medicine, University of Mississippi Medical Center, Jackson, United States

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BibTeX

@article{cheema2026efficacy,
  title = {{Efficacy and safety of low-dose triple and quadruple combination pills for initial hypertension management: a systematic review and meta-analysis of RCTs}},
  author = {Asad Ali Ahmed Cheema and Syed Moiz Abbas and Laiba Nadeem and Hafsa Azam and Ahmed Muneeb Rashid and Khadija Alam and Kumail Mustafa Ali and Abdur Rafay Bilal and Muzamil Hamid Hussain and Chaudhry Saad Sohail and Syed Sarmad Javaid},
  journal = {Annals of medicine and surgery (2012)},
  year = {2026},
  month = oct,
  url = {https://europepmc.org/article/PMC/PMC13754343},
  note = {CC BY},
}

RIS

TY  - JOUR
TI  - Efficacy and safety of low-dose triple and quadruple combination pills for initial hypertension management: a systematic review and meta-analysis of RCTs
AU  - Asad Ali Ahmed Cheema
AU  - Syed Moiz Abbas
AU  - Laiba Nadeem
AU  - Hafsa Azam
AU  - Ahmed Muneeb Rashid
AU  - Khadija Alam
AU  - Kumail Mustafa Ali
AU  - Abdur Rafay Bilal
AU  - Muzamil Hamid Hussain
AU  - Chaudhry Saad Sohail
AU  - Syed Sarmad Javaid
PY  - 2026
DA  - 2026/10/13
JO  - Annals of medicine and surgery (2012)
UR  - https://europepmc.org/article/PMC/PMC13754343
SN  - 2049-0801
ER  -

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