Incidental Detection of Bilateral Node-Positive Papillary Thyroid Carcinoma During Initial Staging for Localized Testicular Seminoma: A Case Report
- 1Department of Endocrine Surgery, Bürgerhospital Frankfurt am Main, Frankfurt am Main, DEU
Abstract
The coexistence of testicular seminoma and papillary thyroid carcinoma (PTC) is uncommon. We report a 32-year-old man with localized pure testicular seminoma treated by right orchiectomy. Staging computed tomography, performed before adjuvant carboplatin, incidentally demonstrated bilateral thyroid lesions. Subsequent evaluation revealed a highly suspicious right thyroid nodule and suspicious cervical lymph nodes. Surgery demonstrated bilateral multifocal PTC with lymphatic invasion and cervical lymph node metastases. Radioiodine therapy was subsequently administered. Comprehensive germline testing using a 90-gene cancer-predisposition panel identified no pathogenic or likely pathogenic variants. The detection of thyroid abnormalities before systemic seminoma treatment makes a treatment-related origin of the PTC highly unlikely. This case highlights the importance of evaluating clinically relevant incidental findings during oncological staging and illustrates the unresolved relationship between testicular germ-cell tumors (TGCTs) and thyroid malignancies.
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BibTeX
@article{farnin2026incidental,
title = {{Incidental Detection of Bilateral Node-Positive Papillary Thyroid Carcinoma During Initial Staging for Localized Testicular Seminoma: A Case Report}},
author = {Roman Farnin and Halil Altindag and Antonia Hammer and Robert Lienenlüke and Johanna Engler and Lula Gebrehiwot and Julian Mittermeier and Andrea Sergio Merlo and Christian Vorländer},
journal = {Cureus},
year = {2026},
month = oct,
doi = {10.7759/cureus.117467},
url = {https://doi.org/10.7759/cureus.117467},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Incidental Detection of Bilateral Node-Positive Papillary Thyroid Carcinoma During Initial Staging for Localized Testicular Seminoma: A Case Report
AU - Roman Farnin
AU - Halil Altindag
AU - Antonia Hammer
AU - Robert Lienenlüke
AU - Johanna Engler
AU - Lula Gebrehiwot
AU - Julian Mittermeier
AU - Andrea Sergio Merlo
AU - Christian Vorländer
PY - 2026
DA - 2026/10/05
JO - Cureus
DO - 10.7759/cureus.117467
UR - https://doi.org/10.7759/cureus.117467
AB - The coexistence of testicular seminoma and papillary thyroid carcinoma (PTC) is uncommon. We report a 32-year-old man with localized pure testicular seminoma treated by right orchiectomy. Staging computed tomography, performed before adjuvant carboplatin, incidentally demonstrated bilateral thyroid lesions. Subsequent evaluation revealed a highly suspicious right thyroid nodule and suspicious cervical lymph nodes. Surgery demonstrated bilateral multifocal PTC with lymphatic invasion and cervical lymph node metastases. Radioiodine therapy was subsequently administered. Comprehensive germline testing using a 90-gene cancer-predisposition panel identified no pathogenic or likely pathogenic variants. The detection of thyroid abnormalities before systemic seminoma treatment makes a treatment-related origin of the PTC highly unlikely. This case highlights the importance of evaluating clinically relevant incidental findings during oncological staging and illustrates the unresolved relationship between testicular germ-cell tumors (TGCTs) and thyroid malignancies.
SN - 2168-8184
ER -