Successful Non-surgical Treatment for a Duodenal Perforation Caused by the Rupture of an Intraductal…

Abstract

An intraductal papillary mucinous neoplasm (IPMN) was incidentally detected in a 91-year-old woman 12 years before her current admission. The patient declined additional examinations and surgical intervention. Over the subsequent years, she experienced recurrent acute pancreatitis and ultimately developed a gastrointestinal perforation due to the rupture of the IPMN. Considering her age, general condition, and personal wishes, conservative management was selected, which allowed her to successfully resume oral intake until death from cancer. This rare clinical course provides valuable insights into the management of older adults with IPMN, a condition that is likely to be frequently encountered as the population ages.

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BibTeX RIS

BibTeX

@article{miyazaki2026successful,
  title = {{Successful Non-surgical Treatment for a Duodenal Perforation Caused by the Rupture of an Intraductal Papillary Mucinous Neoplasm of the Pancreas}},
  author = {Akira Miyazaki and Hiroaki Koike and Keiichi Ito and Kohzoh Makita},
  journal = {Internal Medicine},
  year = {2026},
  month = aug,
  doi = {10.2169/internalmedicine.6315-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/16/65_6315-25/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Successful Non-surgical Treatment for a Duodenal Perforation Caused by the Rupture of an Intraductal Papillary Mucinous Neoplasm of the Pancreas
AU  - Akira Miyazaki
AU  - Hiroaki Koike
AU  - Keiichi Ito
AU  - Kohzoh Makita
PY  - 2026
DA  - 2026/08/15
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6315-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/16/65_6315-25/_article
AB  - An intraductal papillary mucinous neoplasm (IPMN) was incidentally detected in a 91-year-old woman 12 years before her current admission. The patient declined additional examinations and surgical intervention. Over the subsequent years, she experienced recurrent acute pancreatitis and ultimately developed a gastrointestinal perforation due to the rupture of the IPMN. Considering her age, general condition, and personal wishes, conservative management was selected, which allowed her to successfully resume oral intake until death from cancer. This rare clinical course provides valuable insights into the management of older adults with IPMN, a condition that is likely to be frequently encountered as the population ages.
SN  - 1349-7235
SN  - 0918-2918
ER  -

Abstract

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