PreprintarXiv licencearXiv
Simple model of neurogliovascular unit activity with noradrenaline leading force
Abstract
In this work we present a model of a neuroglivascular unit associated with a neuronal ensemble. We combine calcium dynamics in the astrocyte, the cascade of synthesis of arachidonic acid and its derivatives, as well as the activity of the network of inhibitory and excitatory neurons with changes in local blood flow. We add equations to the model for extracellular neurotransmitters such as GABA, glutamate, and norepinephrine. We show that the resulting model can exhibit different types of behavior, and also shows a significant connection between the functioning of the neural network and its supporting components.
Versions
Related
- Dopaminergic Medication Improves Force Control and Modifies Motor Unit Activity During the Steadiest and Least Steady Periods in Parkinsons Disease
- Orbitofrontal noradrenaline supports adaptive learning-rate adjustment in probabilistic reversal learning
- An Integrative Theory of the Noradrenaline System: Meta-Control through Expected Information Gain
- Spatiotemporal characterization of corticolimbic dopamine and noradrenaline signaling and affective state modulation by mfb stimulation
- Topographic structure and function of locus coeruleus noradrenaline neurons
BibTeX
@misc{verisokin2026simple,
title = {{Simple model of neurogliovascular unit activity with noradrenaline leading force}},
author = {Andrey Yu. Verisokin and Darya V. Verveyko and Alexey R. Brazhe and Stanislav V. Lagosha},
howpublished = {arXiv},
year = {2026},
month = oct,
doi = {10.48550/arxiv.2610.15263},
eprint = {2610.15263},
archivePrefix = {arXiv},
url = {https://arxiv.org/abs/2610.15263},
}
RIS
TY - UNPB
TI - Simple model of neurogliovascular unit activity with noradrenaline leading force
AU - Andrey Yu. Verisokin
AU - Darya V. Verveyko
AU - Alexey R. Brazhe
AU - Stanislav V. Lagosha
PY - 2026
DA - 2026/10/11
PB - arXiv
DO - 10.48550/arxiv.2610.15263
UR - https://arxiv.org/abs/2610.15263
AB - In this work we present a model of a neuroglivascular unit associated with a neuronal ensemble. We combine calcium dynamics in the astrocyte, the cascade of synthesis of arachidonic acid and its derivatives, as well as the activity of the network of inhibitory and excitatory neurons with changes in local blood flow. We add equations to the model for extracellular neurotransmitters such as GABA, glutamate, and norepinephrine. We show that the resulting model can exhibit different types of behavior, and also shows a significant connection between the functioning of the neural network and its supporting components.
ER -