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Peer-reviewedCC BY-NC-NDLasers in medical science

Treatment of pyogenic granuloma with a 577-nm diode laser in dark-skinned patients: A prospective case series.

  1. 1Department of Dermatology, Al-Azhar University, Asyut, Egypt. [email protected].

Abstract

Introduction

Pyogenic granulomas are common benign vascular lesions found on exposed skin in children. Treatment in darker skin types can be challenging because of increased epidermal melanin absorption and the associated risk of collateral thermal injury.Objectives

To evaluate the efficacy and safety of a 577-nm diode laser for the treatment of pyogenic granuloma in patients with dark skin types.Patients and methods

Nine patients with pyogenic granuloma and skin types IV-V were enrolled in this prospective case series. They were treated every two weeks with a 577 nm diode laser using a 1 mm spot size, with fluence ranging from 19-23 J/cm2 depending on lesion size until bleeding stopped. Sessions were repeated every two weeks until complete clearance. Patients were followed clinically and photographically every two weeks, and then one month after the final session.Results

This prospective case series included 9 patients clinically diagnosed with pyogenic granuloma. The mean age was 18.0 ± 14.6 years (range, 6-40 years), and the mean duration of pyogenic granuloma was 9.1 ± 3.94 months. Lesions were present on the lips of 4 patients (44.4%), the cheeks in 2 patients (22.2%), hands (2 patients, 22.2%), and neck (1 patient, 11.1%). All patients were treated with a 577 nm diode laser session every 2 weeks until complete clearance. Complete clearance was achieved in 3 patients after the first session, 4 patients after the second session, 1 patient after third session, and only one patient required four treatment sessions. Atrophic scarring was the only reported side effect, occurring in one case.Conclusion

Treatment with a 577-nm diode laser appears to be a safe and effective option for pyogenic granuloma in patients with darker skin types.

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BibTeX
@article{mohamed2026treatment,
  title = {{Treatment of pyogenic granuloma with a 577-nm diode laser in dark-skinned patients: A prospective case series.}},
  author = {Essamelden Mohamed},
  journal = {Lasers in medical science},
  year = {2026},
  month = oct,
  doi = {10.1007/s10103-026-05053-6},
  url = {https://europepmc.org/article/MED/42900353},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Treatment of pyogenic granuloma with a 577-nm diode laser in dark-skinned patients: A prospective case series.
AU  - Essamelden Mohamed
PY  - 2026
DA  - 2026/10/20
JO  - Lasers in medical science
DO  - 10.1007/s10103-026-05053-6
UR  - https://europepmc.org/article/MED/42900353
AB  - Introduction  Pyogenic granulomas are common benign vascular lesions found on exposed skin in children. Treatment in darker skin types can be challenging because of increased epidermal melanin absorption and the associated risk of collateral thermal injury.Objectives  To evaluate the efficacy and safety of a 577-nm diode laser for the treatment of pyogenic granuloma in patients with dark skin types.Patients and methods  Nine patients with pyogenic granuloma and skin types IV-V were enrolled in this prospective case series. They were treated every two weeks with a 577 nm diode laser using a 1 mm spot size, with fluence ranging from 19-23 J/cm2 depending on lesion size until bleeding stopped. Sessions were repeated every two weeks until complete clearance. Patients were followed clinically and photographically every two weeks, and then one month after the final session.Results  This prospective case series included 9 patients clinically diagnosed with pyogenic granuloma. The mean age was 18.0 ± 14.6 years (range, 6-40 years), and the mean duration of pyogenic granuloma was 9.1 ± 3.94 months. Lesions were present on the lips of 4 patients (44.4%), the cheeks in 2 patients (22.2%), hands (2 patients, 22.2%), and neck (1 patient, 11.1%). All patients were treated with a 577 nm diode laser session every 2 weeks until complete clearance. Complete clearance was achieved in 3 patients after the first session, 4 patients after the second session, 1 patient after third session, and only one patient required four treatment sessions. Atrophic scarring was the only reported side effect, occurring in one case.Conclusion  Treatment with a 577-nm diode laser appears to be a safe and effective option for pyogenic granuloma in patients with darker skin types.
SN  - 0268-8921
SN  - 1435-604X
ER  -