Outcomes of isolated hip fractures in people with Parkinson's disease: An observational cohort study using propensity score methods.
8 affiliations
- 1Physiotherapy Department, The University of Melbourne, Parkville, Australia.
- 2Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
- 3School of Public Health and Preventive Medicine, Monash University, Clayton, Australia.
- 4Physiotherapy Department, The Alfred Hospital, Prahran, Australia.
- 5Fight Parkinson's, Melbourne, Camberwell, Australia.
- 6Physiotherapy Department, Austin Health, Heidelberg, Australia.
- 7Eastern Health Clinical School, Monash University, Boxhill, Australia.
- 8Department of Medicine, Monash University, Clayton, VIC, Australia.
Abstract
BackgroundPeople with Parkinson's disease (PwP) have a high risk of hip fracture and the outcomes of PwP in Australia with hip fractures are unknown.ObjectiveTo describe the characteristics of PwP who present with a hip fracture and to examine the association between Parkinson's with acute hospital outcomes, mortality and discharge destination.MethodsWe conducted a cohort study of individuals with an isolated proximal femur fracture using the Victorian Orthopaedic Trauma Outcomes Registry (Australia) from 2016 to 2022. Demographic characteristics, comorbidities, fracture types, acute hospital length of stay, discharge destination and 30-day and 12-month mortality data were extracted. Inverse-probability weighting with estimated propensity scores determined the association of Parkinson's with outcomes, using a logistic regression model that included covariates and injury characteristics.ResultsOf 5,553 patients, 208 (4%) had PD, with a mean age of 79.9 years (SD 12.9). After propensity score adjustment, there was no association between Parkinson's and ICU admission (OR 1.89; 95% CI 0.67, 5.34), acute length of stay (adjusted median 6.9 vs 7.7) and 12-month mortality rates (OR 1.25; 95% CI 0.85, 1.82). PwP were more likely to be discharged to rehabilitation than home (RR 2.04; 95% CI 1.12, 3.74).ConclusionsWe did not observe a statistically significant difference in acute hospital outcomes between the two cohorts, including length of stay. This is encouraging as avoiding prolonged hospitalisation reduces health care costs and risk of hospital-related harms. However, these findings may reflect limited statistical power and differences between groups cannot be excluded. Further research is also indicated to explore post-care discharge pathways and longer-term functional outcomes of this group.
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BibTeX
@article{mcginley2026outcomes,
title = {{Outcomes of isolated hip fractures in people with Parkinson's disease: An observational cohort study using propensity score methods.}},
author = {Jennifer L McGinley and Michele Callisaya and Belinda Gabbe and Kate Behm and Victor McConvey and Jennifer Jones and Raphael Hau and Mícheál Ó Breasail and Sze-Ee Soh},
journal = {Journal of Parkinson's disease},
year = {2026},
month = oct,
doi = {10.1177/1877718x261499245},
url = {https://europepmc.org/article/MED/42911098},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Outcomes of isolated hip fractures in people with Parkinson's disease: An observational cohort study using propensity score methods.
AU - Jennifer L McGinley
AU - Michele Callisaya
AU - Belinda Gabbe
AU - Kate Behm
AU - Victor McConvey
AU - Jennifer Jones
AU - Raphael Hau
AU - Mícheál Ó Breasail
AU - Sze-Ee Soh
PY - 2026
DA - 2026/10/22
JO - Journal of Parkinson's disease
DO - 10.1177/1877718x261499245
UR - https://europepmc.org/article/MED/42911098
AB - BackgroundPeople with Parkinson's disease (PwP) have a high risk of hip fracture and the outcomes of PwP in Australia with hip fractures are unknown.ObjectiveTo describe the characteristics of PwP who present with a hip fracture and to examine the association between Parkinson's with acute hospital outcomes, mortality and discharge destination.MethodsWe conducted a cohort study of individuals with an isolated proximal femur fracture using the Victorian Orthopaedic Trauma Outcomes Registry (Australia) from 2016 to 2022. Demographic characteristics, comorbidities, fracture types, acute hospital length of stay, discharge destination and 30-day and 12-month mortality data were extracted. Inverse-probability weighting with estimated propensity scores determined the association of Parkinson's with outcomes, using a logistic regression model that included covariates and injury characteristics.ResultsOf 5,553 patients, 208 (4%) had PD, with a mean age of 79.9 years (SD 12.9). After propensity score adjustment, there was no association between Parkinson's and ICU admission (OR 1.89; 95% CI 0.67, 5.34), acute length of stay (adjusted median 6.9 vs 7.7) and 12-month mortality rates (OR 1.25; 95% CI 0.85, 1.82). PwP were more likely to be discharged to rehabilitation than home (RR 2.04; 95% CI 1.12, 3.74).ConclusionsWe did not observe a statistically significant difference in acute hospital outcomes between the two cohorts, including length of stay. This is encouraging as avoiding prolonged hospitalisation reduces health care costs and risk of hospital-related harms. However, these findings may reflect limited statistical power and differences between groups cannot be excluded. Further research is also indicated to explore post-care discharge pathways and longer-term functional outcomes of this group.
SN - 1877-7171
SN - 1877-718X
ER -