Skip to content
DraconiticResearch
Search Sources API
182,469 studies31 sourcesUpdated 32 min ago
Peer-reviewedCC BY-NCAtencion primaria

[Appropriateness of strong opioid prescribing chronic non-cancer pain in primary care: a cross-sectional study].

  • Jorge Díaz-Piñeiro1
  • José Ignacio González-González2
  • Eric Bismar Infante-Peralta3
  • Miguel Solís-González1
  • Luis Solís-González4
  • Guillermo Palomar-Ramos5
5 affiliations
  1. 1Centro de Salud Las Vegas, Área Sanitaria III, Servicio de Salud del Principado de Asturias, Corvera de Asturias, Asturias, España.
  2. 2Centro de Salud de Pravia, Área Sanitaria III, Servicio de Salud del Principado de Asturias, Pravia, Asturias, España.
  3. 3Centro de Salud Sabugo, Área Sanitaria III, Servicio de Salud del Principado de Asturias, Avilés, Asturias, España.
  4. 4Gerencia de Mieres Sur, Área Sanitaria VII, Servicio de Salud del Principado de Asturias, Mieres, Asturias, España. Electronic address: [email protected].
  5. 5Universitätsspital Zürich (USZ), University of Zurich, Zúrich, Suiza.
Read full textPDFDOICite

Abstract

Objective

To assess the appropriateness of strong opioid prescribing for chronic non-cancer pain (CNCP) in primary care and to analyse factors associated with inappropriate prescribing.Design

Cross-sectional observational study. SITE: Three primary care centres in a health area in northern Spain.Participants

Active prescriptions of strong opioids in adult patients with CNCP. A total of 441 prescriptions corresponding to 387 patients were analysed.Interventions

No interventions were performed. A retrospective review of prescriptions and electronic health records was conducted.Main measurements

Therapeutic appropriateness according to eight clinical recommendations on indication, previous analgesic escalation, concomitant treatment and safety. Descriptive analysis and multivariable logistic regression were performed.Results

Mean age was 67.1years (SD: 16.0), and 71.4% of prescriptions corresponded to women. Overall, 82.8% of prescriptions were considered inappropriate. The most frequent non-adherence criterion was concomitant benzodiazepine use (55.1%). In the multivariable model, age (OR: 1.02; 95%CI: 1.00-1.04; P=.038) and concomitant antidepressant treatment (OR: 4.76; 95%CI: 2.17-10.64; P<.001) were associated with inappropriate prescribing. A high-risk clinical profile was observed in 31.5% of prescriptions.Conclusions

Strong opioid prescribing for CNCP showed a high proportion of inappropriate use. These findings support the implementation of prescribing review and medication safety interventions in primary care.

Related

  1. Patterns and appropriateness of antipsychotic prescribing in community-dwelling older adults: a retrospective study
    Khalid A. Alamer, Dana Alsugeir, Fawaz M. Alotaibi +11
    Frontiers in pharmacologyPeer-reviewedCC BYFull textPharmacology & toxicologyEurope PMC
  2. Appropriateness of antibiotic prescribing in dental practice: results of two clinical audits conducted at a university hospital
    Romain Lan, Célia Lento, Delphine Tardivo +6
    Frontiers in Oral HealthPeer-reviewedCC BY 4.0Full textGeneral biologyEpidemiology & public healthHAL
  3. Role of patient sex in prescribing long-term beta blockers after myocardial infarction in German-speaking European primary care settings: a cross-sectional online survey using case vignettes
    Rahel Grindat, Katharina T Jungo, Kali Tal +6
    BMJ OpenPeer-reviewedCC BY 4.0Full textCardiovascular medicineCrossrefPMC
  4. Case-mix-adjusted benchmarking of musculoskeletal outcomes and opioid prescribing in English primary care: a prospective cohort study
    Jonathan C Hill, Dahai Yu, Kelvin P Jordan +8
    BMJ OpenPeer-reviewedCC BY-NC 4.0Full textGeneral medicineCrossref
  5. Factors influencing access to green health prescribing in primary care for older adults – a qualitative systematic review
    Jeremiah Donoghue, Furqan Butt, Cameron Ley +10
    BMC MedicinePeer-reviewedCC BY-NC-ND 4.0Full text1 citedPharmacology & toxicologyCrossref

Cite

BibTeXRIS
BibTeX
@article{diazpineiro2026appropriateness,
  title = {{[Appropriateness of strong opioid prescribing chronic non-cancer pain in primary care: a cross-sectional study].}},
  author = {Jorge Díaz-Piñeiro and José Ignacio González-González and Eric Bismar Infante-Peralta and Miguel Solís-González and Luis Solís-González and Guillermo Palomar-Ramos},
  journal = {Atencion primaria},
  year = {2026},
  month = oct,
  doi = {10.1016/j.aprim.2026.103601},
  url = {https://europepmc.org/article/MED/42874373},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - [Appropriateness of strong opioid prescribing chronic non-cancer pain in primary care: a cross-sectional study].
AU  - Jorge Díaz-Piñeiro
AU  - José Ignacio González-González
AU  - Eric Bismar Infante-Peralta
AU  - Miguel Solís-González
AU  - Luis Solís-González
AU  - Guillermo Palomar-Ramos
PY  - 2026
DA  - 2026/10/14
JO  - Atencion primaria
DO  - 10.1016/j.aprim.2026.103601
UR  - https://europepmc.org/article/MED/42874373
AB  - Objective  To assess the appropriateness of strong opioid prescribing for chronic non-cancer pain (CNCP) in primary care and to analyse factors associated with inappropriate prescribing.Design  Cross-sectional observational study. SITE: Three primary care centres in a health area in northern Spain.Participants  Active prescriptions of strong opioids in adult patients with CNCP. A total of 441 prescriptions corresponding to 387 patients were analysed.Interventions  No interventions were performed. A retrospective review of prescriptions and electronic health records was conducted.Main measurements  Therapeutic appropriateness according to eight clinical recommendations on indication, previous analgesic escalation, concomitant treatment and safety. Descriptive analysis and multivariable logistic regression were performed.Results  Mean age was 67.1years (SD: 16.0), and 71.4% of prescriptions corresponded to women. Overall, 82.8% of prescriptions were considered inappropriate. The most frequent non-adherence criterion was concomitant benzodiazepine use (55.1%). In the multivariable model, age (OR: 1.02; 95%CI: 1.00-1.04; P=.038) and concomitant antidepressant treatment (OR: 4.76; 95%CI: 2.17-10.64; P<.001) were associated with inappropriate prescribing. A high-risk clinical profile was observed in 31.5% of prescriptions.Conclusions  Strong opioid prescribing for CNCP showed a high proportion of inappropriate use. These findings support the implementation of prescribing review and medication safety interventions in primary care.
SN  - 0212-6567
SN  - 1578-1275
ER  -