Cellulose acetate nanoparticles: impacts of concentration and exposure time on the biochemistry and hematology of juvenile Colossoma macropomum.
4 affiliations
- 1Department of Metallurgical and Materials Engineering, Federal University of Minas Gerais (UFMG), Av. Antônio Carlos, 6627 - Campus da UFMG, Pampulha, Belo Horizonte, MG, Brazil. [email protected].
- 2Department of Metallurgical and Materials Engineering, Federal University of Minas Gerais (UFMG), Av. Antônio Carlos, 6627 - Campus da UFMG, Pampulha, Belo Horizonte, MG, Brazil.
- 3Departamento de Zootecnia, Laboratório de Aquacultura, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, n° 6627, Belo Horizonte, CEP 30161- 970, MG, Brazil.
- 4Department of Engineering, Federal University of Lavras, PO Box 3037, Lavras, 372000-900, MG, Brazil.
Abstract
This study evaluated the physiological impacts of acute-exposure of tambaqui (Colossoma macropomum) to different concentrations of cellulose acetate nanoparticles at different sampling times. A total of 120 juvenile C. macropomum (38.91 ± 5.57 g and 13.76 ± 0.74 cm in total length) were distributed in 12 tanks of 150 L, in a recirculating aquaculture system (RAS). The juveniles were kept in water containing cellulose acetate nanoparticles (CANs) at four different concentrations (treatments): 0 mg L⁻¹, 0.01 mg L⁻¹, 0.10 mg L⁻¹ and 1.00 mg L⁻¹. Blood samples were collected after 1 and 24 h of exposure. The juveniles were then relocated to a tank with clean water, where they remained for another 24 h, after which a new blood sample was collected (24 h). Hemoglobin, serum protein and globulin were reduced after 1 h of exposure for the group exposed to 1.00 mg L⁻¹ of CANs. Glucose levels increased after 24 h for the groups exposed to 0.10 and 1.00 mg L⁻¹. Urea increased after 1 h for the groups exposed to 0.10 and 1.00 mg L⁻¹. Triglycerides and cholesterol were reduced both after 1 h and 24 h of exposure for the 1.00 mg L⁻¹ group, returning to baseline levels at 24 h. The activities of aspartate aminotransferase (AST) and alanine aminotransferase were altered after 24 h. Albumin was lower after 1 h and 24 h compared to after 24 h for the 1.00 mg L⁻¹ group. Exposure of juvenile C. macropomum to CANs caused transient physiological changes, with partial recovery being observed after transfer to clean water.
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BibTeX
@article{oliveira2026cellulose,
title = {{Cellulose acetate nanoparticles: impacts of concentration and exposure time on the biochemistry and hematology of juvenile Colossoma macropomum.}},
author = {Camila Gomes de Oliveira and Túlio Pacheco Boaventura and Fábio Aremil Costa Dos Santos and André de Sena Souza and Sidney Dos Santos Silva and Imaculada de Morais Carvalho Ananias and Camila Silva Brey Gil and Ronald Kennedy Luz and Rodrigo Lambert Oréfice},
journal = {Ecotoxicology (London, England)},
year = {2026},
month = oct,
doi = {10.1007/s10646-026-03174-w},
url = {https://europepmc.org/article/MED/42909697},
note = {CC BY},
}
RIS
TY - JOUR
TI - Cellulose acetate nanoparticles: impacts of concentration and exposure time on the biochemistry and hematology of juvenile Colossoma macropomum.
AU - Camila Gomes de Oliveira
AU - Túlio Pacheco Boaventura
AU - Fábio Aremil Costa Dos Santos
AU - André de Sena Souza
AU - Sidney Dos Santos Silva
AU - Imaculada de Morais Carvalho Ananias
AU - Camila Silva Brey Gil
AU - Ronald Kennedy Luz
AU - Rodrigo Lambert Oréfice
PY - 2026
DA - 2026/10/23
JO - Ecotoxicology (London, England)
DO - 10.1007/s10646-026-03174-w
UR - https://europepmc.org/article/MED/42909697
AB - This study evaluated the physiological impacts of acute-exposure of tambaqui (Colossoma macropomum) to different concentrations of cellulose acetate nanoparticles at different sampling times. A total of 120 juvenile C. macropomum (38.91 ± 5.57 g and 13.76 ± 0.74 cm in total length) were distributed in 12 tanks of 150 L, in a recirculating aquaculture system (RAS). The juveniles were kept in water containing cellulose acetate nanoparticles (CANs) at four different concentrations (treatments): 0 mg L⁻¹, 0.01 mg L⁻¹, 0.10 mg L⁻¹ and 1.00 mg L⁻¹. Blood samples were collected after 1 and 24 h of exposure. The juveniles were then relocated to a tank with clean water, where they remained for another 24 h, after which a new blood sample was collected (24 h). Hemoglobin, serum protein and globulin were reduced after 1 h of exposure for the group exposed to 1.00 mg L⁻¹ of CANs. Glucose levels increased after 24 h for the groups exposed to 0.10 and 1.00 mg L⁻¹. Urea increased after 1 h for the groups exposed to 0.10 and 1.00 mg L⁻¹. Triglycerides and cholesterol were reduced both after 1 h and 24 h of exposure for the 1.00 mg L⁻¹ group, returning to baseline levels at 24 h. The activities of aspartate aminotransferase (AST) and alanine aminotransferase were altered after 24 h. Albumin was lower after 1 h and 24 h compared to after 24 h for the 1.00 mg L⁻¹ group. Exposure of juvenile C. macropomum to CANs caused transient physiological changes, with partial recovery being observed after transfer to clean water.
SN - 0963-9292
SN - 1573-3017
ER -