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Peer-reviewedCC BY 4.0Molecules

Isolation and Structural Characterization of Two New Xanthone Derivatives from the Marine-Derived Fungus Penicillium sp. F28

  1. 1Morphological Center, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China
  2. 2Hainan Key Laboratory of Tropical Microbe Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences Key Laboratory for Biology and Genetic Resources of Tropical Crops of Hainan Province, Hainan Institute for Tropical Agricultural Resources, Haikou 571101, China
  3. 3Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou 571126, China

Abstract

Eight compounds, including two new compounds, xishaxanthone A (1) and xishaxanthone B (2), and six known compounds (3–8), were isolated from the marine-derived fungus Penicillium sp. F28 and structurally characterized. Xishaxanthone A (1) is a new xanthone derivative which possesses a 1,7-dihydroxanthone skeleton with a methyl carboxylate group at C-8, a substitution pattern rarely encountered among xanthone natural products. The structure was determined by a combination of techniques including HR-ESI-MS (High-Resolution Electrospray Ionization Mass Spectrometry), NMR (Nuclear Magnetic Resonance), and ECD (Electronic Circular Dichroism) calculations. Furthermore, a hypothetical biosynthetic pathway for compound 1 is proposed.

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BibTeX
@article{abulaizi2026isolation,
  title = {{Isolation and Structural Characterization of Two New Xanthone Derivatives from the Marine-Derived Fungus Penicillium sp. F28}},
  author = {Ailiman Abulaizi and Jingzhe Yuan and Zijun Xiong and Shiqing Zhang and Rong Wang and Shuai Ma and Zhikai Guo},
  journal = {Molecules},
  year = {2026},
  month = oct,
  doi = {10.3390/molecules31213820},
  url = {https://www.mdpi.com/1420-3049/31/21/3820},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Isolation and Structural Characterization of Two New Xanthone Derivatives from the Marine-Derived Fungus Penicillium sp. F28
AU  - Ailiman Abulaizi
AU  - Jingzhe Yuan
AU  - Zijun Xiong
AU  - Shiqing Zhang
AU  - Rong Wang
AU  - Shuai Ma
AU  - Zhikai Guo
PY  - 2026
DA  - 2026/10/23
JO  - Molecules
DO  - 10.3390/molecules31213820
UR  - https://www.mdpi.com/1420-3049/31/21/3820
AB  - Eight compounds, including two new compounds, xishaxanthone A (1) and xishaxanthone B (2), and six known compounds (3–8), were isolated from the marine-derived fungus Penicillium sp. F28 and structurally characterized. Xishaxanthone A (1) is a new xanthone derivative which possesses a 1,7-dihydroxanthone skeleton with a methyl carboxylate group at C-8, a substitution pattern rarely encountered among xanthone natural products. The structure was determined by a combination of techniques including HR-ESI-MS (High-Resolution Electrospray Ionization Mass Spectrometry), NMR (Nuclear Magnetic Resonance), and ECD (Electronic Circular Dichroism) calculations. Furthermore, a hypothetical biosynthetic pathway for compound 1 is proposed.
SN  - 1420-3049
ER  -