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PreprintCC BYbioRxiv

dictyExpress: an integrated browser for bulk and single-cell Dictyostelium transcriptomics

  1. 1University of Ljubljana

Abstract

Summary dictyExpress 3.0 is a React/TypeScript reimplementation of the Dictyostelium discoideum transcriptomics web server, first introduced in 2009, that unifies bulk and single-cell exploration. A long-standing gene-expression resource for the Dictyostelium community, dictyExpress is also accessible through dictyBase, the central organism database for Dictyostelium. The new release preserves the curated bulk RNA-seq dashboards of earlier versions while adding an interactive module for a developmental scRNA-seq time course of wild-type AX4 and two cAMP-signalling mutants. Following visual analytics principles, interactive visualizations are coordinated through brushing and linking, with bulk time courses, differential expression, gene-ontology enrichment and the UMAP workspace sharing a common gene selection, enabling bookmarkable and exportable cross-modal analysis in one interface for Dictyostelium transcriptomics. Availability and implementation dictyExpress is available at https://app.dictyexpress.org/. Source code: https://github.com/biolab/dictyexpress-js. Contact [email protected], [email protected]

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BibTeX
@misc{trnovec2026dictyexpress,
  title = {{dictyExpress: an integrated browser for bulk and single-cell Dictyostelium transcriptomics}},
  author = {L. Trnovec and M. Stajdohar and G. Shaulsky and B. Zupan},
  howpublished = {bioRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.04.748563},
  url = {https://www.biorxiv.org/content/10.64898/2026.09.04.748563v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - dictyExpress: an integrated browser for bulk and single-cell Dictyostelium transcriptomics
AU  - L. Trnovec
AU  - M. Stajdohar
AU  - G. Shaulsky
AU  - B. Zupan
PY  - 2026
DA  - 2026/09/04
PB  - bioRxiv
DO  - 10.64898/2026.09.04.748563
UR  - https://www.biorxiv.org/content/10.64898/2026.09.04.748563v1
AB  - Summary dictyExpress 3.0 is a React/TypeScript reimplementation of the Dictyostelium discoideum transcriptomics web server, first introduced in 2009, that unifies bulk and single-cell exploration. A long-standing gene-expression resource for the Dictyostelium community, dictyExpress is also accessible through dictyBase, the central organism database for Dictyostelium. The new release preserves the curated bulk RNA-seq dashboards of earlier versions while adding an interactive module for a developmental scRNA-seq time course of wild-type AX4 and two cAMP-signalling mutants. Following visual analytics principles, interactive visualizations are coordinated through brushing and linking, with bulk time courses, differential expression, gene-ontology enrichment and the UMAP workspace sharing a common gene selection, enabling bookmarkable and exportable cross-modal analysis in one interface for Dictyostelium transcriptomics. Availability and implementation dictyExpress is available at https://app.dictyexpress.org/. Source code: https://github.com/biolab/dictyexpress-js. Contact [email protected], [email protected]
ER  -