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Peer-reviewedCC BY-NC-ND 4.0Journal of Infection

A Rapid and simple method for quantifying rezafungin in human plasma

  • Eyrian Aubin-Beale
  • Maxime Kolmayer
  • Alan Kolodziej
  • Heiko Palma
  • Emmanuel Novy
  • Pierre Gillet
  • Elise Pape
  • Julien Scala-Bertola
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Abstract

There is no fully described method in the literature for quantifying rezafungin in human plasma or other biological matrices. Most in vivo or clinical studies investigating rezafungin specify only brief analytical methodological details. In our university hospital, we have adapted the ready-to-use commercial kit developed by ChromSystems for therapeutic monitoring of several antifungal agents in plasma for use with rezafungin. This industrial-grade analytical method can be implemented quickly and easily in medical laboratories equipped with a chromatographic system coupled with a tandem mass spectrometer.

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Cite

BibTeXRIS
BibTeX
@article{aubinbeale2026rapid,
  title = {{A Rapid and simple method for quantifying rezafungin in human plasma}},
  author = {Eyrian Aubin-Beale and Maxime Kolmayer and Alan Kolodziej and Heiko Palma and Emmanuel Novy and Pierre Gillet and Elise Pape and Julien Scala-Bertola},
  journal = {Journal of Infection},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jinf.2026.106867},
  url = {https://hal.science/hal-05773192v1},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - A Rapid and simple method for quantifying rezafungin in human plasma
AU  - Eyrian Aubin-Beale
AU  - Maxime Kolmayer
AU  - Alan Kolodziej
AU  - Heiko Palma
AU  - Emmanuel Novy
AU  - Pierre Gillet
AU  - Elise Pape
AU  - Julien Scala-Bertola
PY  - 2026
DA  - 2026/09/26
JO  - Journal of Infection
DO  - 10.1016/j.jinf.2026.106867
UR  - https://hal.science/hal-05773192v1
AB  - There is no fully described method in the literature for quantifying rezafungin in human plasma or other biological matrices. Most in vivo or clinical studies investigating rezafungin specify only brief analytical methodological details. In our university hospital, we have adapted the ready-to-use commercial kit developed by ChromSystems for therapeutic monitoring of several antifungal agents in plasma for use with rezafungin. This industrial-grade analytical method can be implemented quickly and easily in medical laboratories equipped with a chromatographic system coupled with a tandem mass spectrometer.
SN  - 0163-4453
SN  - 1532-2742
ER  -