Total Hip Arthroplasty in a Patient With Alpha-Gal Syndrome.
- 1Tufts University School of Medicine, Boston, MA, USA.
- 2MMP Orthopaedics & Sports Medicine, Maine Medical Center, Portland, ME, USA.
- 3Department of Anesthesiology, Maine Medical Center, Portland, ME, USA.
Abstract
Alpha-gal syndrome (AGS) is an IgE-mediated reaction against galactose-ɑ-1,3-galactose, an oligosaccharide found in mammalian-derived foods and numerous medications containing animal products. AGS is an acquired condition brought about by a tick-borne illness that is increasing in prevalence in the United States. Managing this condition is particularly challenging in the surgical setting, where many commonly used hemostatic and analgesic agents contain animal-derived inactive ingredients. We describe a multidisciplinary approach taken to prevent triggering an allergic reaction in a patient with AGS who underwent total hip arthroplasty leading to a successful recovery. This case highlights important perioperative considerations in patients with AGS and describes a safe pathway to successful arthroplasty in this high-risk population.
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BibTeX
@article{faour2026total,
title = {{Total Hip Arthroplasty in a Patient With Alpha-Gal Syndrome.}},
author = {Kamli N W Faour and Brian J McGrory and Christopher Kunkel and Danielle Kerr},
journal = {Arthroplasty today},
year = {2026},
month = oct,
doi = {10.1016/j.artd.2026.102133},
url = {https://europepmc.org/article/MED/42909069},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Total Hip Arthroplasty in a Patient With Alpha-Gal Syndrome.
AU - Kamli N W Faour
AU - Brian J McGrory
AU - Christopher Kunkel
AU - Danielle Kerr
PY - 2026
DA - 2026/10/14
JO - Arthroplasty today
DO - 10.1016/j.artd.2026.102133
UR - https://europepmc.org/article/MED/42909069
AB - Alpha-gal syndrome (AGS) is an IgE-mediated reaction against galactose-ɑ-1,3-galactose, an oligosaccharide found in mammalian-derived foods and numerous medications containing animal products. AGS is an acquired condition brought about by a tick-borne illness that is increasing in prevalence in the United States. Managing this condition is particularly challenging in the surgical setting, where many commonly used hemostatic and analgesic agents contain animal-derived inactive ingredients. We describe a multidisciplinary approach taken to prevent triggering an allergic reaction in a patient with AGS who underwent total hip arthroplasty leading to a successful recovery. This case highlights important perioperative considerations in patients with AGS and describes a safe pathway to successful arthroplasty in this high-risk population.
SN - 2352-3441
ER -