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Peer-reviewedCC BY-NC-ND 4.0Radiology Case Reports

Bilateral synchronous juvenile breast papillomatosis: A case report and review of the literature

  • Kawtar Lahlali1
  • Oumayma Lahjouji1
  • Hajar Ouazzani1
  • Ismail Chaouche1
  • Amal Akammar1
  • Nizar El Bouardi1
  • Meryam Haloua1
  • Badr Alami1
  • Moulay Youssef Alaoui Lamrani1
  • Mustapha Maaroufi1
  • Meryem Boubbou1
  1. 1Department of radiology, CHU Hassan II, Sidi Mohammed Ben, Abdellah University, FEZ, Morocco
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Abstract

Juvenile papillomatosis (JP) is a rare benign breast disorder primarily affecting young women. It is characterized by atypical papillary duct hyperplasia and multiple cysts, and was first described as a distinct clinicopathologic entity in 1980.

We report the case of an 17-year-old woman with no significant personal or family history of breast cancer, who presented with a sero-hemorrhagic nipple discharge from the right breast for four years. Clinical examination revealed no palpable masses.

Ultrasound and MRI revealed a dilated galactophoric duct surrounded by cystic lesions in the upper outer quadrant of the right breast and at the junction of the inner quadrants of the left breast, consistent with bilateral juvenile papillomatosis.

The patient underwent a right breast pyramidectomy. Histopathological examination showed cystic dilatation of the galactophoric ducts on a fibrous breast parenchyma, with moderate hyperplasia without atypia, suggestive of the diagnosis.

Breast-conserving surgery is planned for the left breast.

Juvenile papillomatosis is an exceptionally rare benign breast lesion occurring in young women. Radiological imaging is essential for lesion detection, while histopathological examination remains the gold standard for diagnosis.

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Cite

BibTeXRIS
BibTeX
@article{lahlali2026bilateral,
  title = {{Bilateral synchronous juvenile breast papillomatosis: A case report and review of the literature}},
  author = {Kawtar Lahlali and Oumayma Lahjouji and Hajar Ouazzani and Ismail Chaouche and Amal Akammar and Nizar El Bouardi and Meryam Haloua and Badr Alami and Moulay Youssef Alaoui Lamrani and Mustapha Maaroufi and Meryem Boubbou},
  journal = {Radiology Case Reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.radcr.2026.09.080},
  url = {https://doi.org/10.1016/j.radcr.2026.09.080},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Bilateral synchronous juvenile breast papillomatosis: A case report and review of the literature
AU  - Kawtar Lahlali
AU  - Oumayma Lahjouji
AU  - Hajar Ouazzani
AU  - Ismail Chaouche
AU  - Amal Akammar
AU  - Nizar El Bouardi
AU  - Meryam Haloua
AU  - Badr Alami
AU  - Moulay Youssef Alaoui Lamrani
AU  - Mustapha Maaroufi
AU  - Meryem Boubbou
PY  - 2026
DA  - 2026/10/17
JO  - Radiology Case Reports
DO  - 10.1016/j.radcr.2026.09.080
UR  - https://doi.org/10.1016/j.radcr.2026.09.080
AB  - Juvenile papillomatosis (JP) is a rare benign breast disorder primarily affecting young women. It is characterized by atypical papillary duct hyperplasia and multiple cysts, and was first described as a distinct clinicopathologic entity in 1980.  We report the case of an 17-year-old woman with no significant personal or family history of breast cancer, who presented with a sero-hemorrhagic nipple discharge from the right breast for four years. Clinical examination revealed no palpable masses.  Ultrasound and MRI revealed a dilated galactophoric duct surrounded by cystic lesions in the upper outer quadrant of the right breast and at the junction of the inner quadrants of the left breast, consistent with bilateral juvenile papillomatosis.  The patient underwent a right breast pyramidectomy. Histopathological examination showed cystic dilatation of the galactophoric ducts on a fibrous breast parenchyma, with moderate hyperplasia without atypia, suggestive of the diagnosis.  Breast-conserving surgery is planned for the left breast.  Juvenile papillomatosis is an exceptionally rare benign breast lesion occurring in young women. Radiological imaging is essential for lesion detection, while histopathological examination remains the gold standard for diagnosis.
SN  - 1930-0433
ER  -