PreprintAll rights reservedbioRxiv
The human-specific lncRNA HD-LINC drives lipid droplet-associated neurodegeneration in Huntington's disease
- 1Department of Developmental Biology, Washington University in St. Louis
Related
- Cas9 nickase–mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington’s disease mouse model
- Synonymous HTT CAA/CCA-loss variants associated with early Huntington disease onset enhance toxicity beyond somatic instability
- Emotion regulation difficulties are selectively associated with executive and behavioural apathy in Huntington's disease.
- Depletion of border-associated macrophages impairs CSF flow and exacerbates extranuclear mutant Huntingtin aggregation in the zQ175DN mouse model of Huntington’s disease
- Restoring Aquaporin-4 alleviates molecular and motor phenotypes in zQ175 mouse model of Huntington disease
BibTeX
@misc{kwon2026humanspecific,
title = {{The human-specific lncRNA HD-LINC drives lipid droplet-associated neurodegeneration in Huntington's disease}},
author = {J.-S. Kwon and L. Wang and N. R. Ganti and J. Li and S. Xia and O. Al-Dalahmah and A. S. Yoo},
howpublished = {bioRxiv},
year = {2026},
month = oct,
doi = {10.64898/2026.10.23.761349},
url = {https://www.biorxiv.org/content/10.64898/2026.10.23.761349v1},
}
RIS
TY - UNPB
TI - The human-specific lncRNA HD-LINC drives lipid droplet-associated neurodegeneration in Huntington's disease
AU - J.-S. Kwon
AU - L. Wang
AU - N. R. Ganti
AU - J. Li
AU - S. Xia
AU - O. Al-Dalahmah
AU - A. S. Yoo
PY - 2026
DA - 2026/10/23
PB - bioRxiv
DO - 10.64898/2026.10.23.761349
UR - https://www.biorxiv.org/content/10.64898/2026.10.23.761349v1
ER -