State-of-the-Art Review: Transjugular Tricuspid Valve Replacement Using the LuX-Valve Plus System
Abstract
Severe tricuspid regurgitation remains a major therapeutic challenge, particularly in patients with extensive annular dilation or advanced right heart remodeling. Transcatheter tricuspid valve replacement(TTVR) has emerged as a promising alternative for anatomically complex and high‑risk patients who are not suitable for surgery or transcatheter edge‑to‑edge repair. Among currently available systems, the LuX‑Valve Plus device offers a unique transjugular approach and anchoring strategy. This state‑of‑the‑art review provides a comprehensive overview of the LuX‑Valve Plus system, including technical characteristics, procedural steps, multimodality imaging guidance, and key anatomical considerations for patient selection. Drawing on current literature and expert experience, the review describes a step‑by‑step procedural framework with a focus on anatomical screening, computed tomography-based planning, intraprocedural three‑dimensional transesophageal echocardiography, and the use of advanced imaging modalities such as fusion imaging. Practical tips are provided to optimize device positioning, septal anchoring, and leaflet interaction in the setting of highly variable anatomy. Overall, the LuX‑Valve Plus system broadens the spectrum of TTVR to anatomically challenging patients, and this review offers a practical guide for clinicians by offering detailed technical insights, imaging protocols, and procedural strategies essential for successful implantation and avoidance of complications.
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BibTeX
@article{donal2026stateoftheart,
title = {{State-of-the-Art Review: Transjugular Tricuspid Valve Replacement Using the LuX-Valve Plus System}},
author = {Erwan Donal and Augustin Coisne and Julien Ternacle and Guillaume L'Official and Julien Dreyfus and Mohammed Nejjari and Lionel Leroux and Ole de Backer and Azeem Latib and Juan F. Granada and Ralph Stephan von Bardeleben and Thomas Modine},
journal = {Structural Heart},
year = {2026},
month = oct,
doi = {10.1016/j.shj.2026.100792},
url = {https://hal.science/hal-05830446v1},
note = {CC BY},
}
RIS
TY - JOUR
TI - State-of-the-Art Review: Transjugular Tricuspid Valve Replacement Using the LuX-Valve Plus System
AU - Erwan Donal
AU - Augustin Coisne
AU - Julien Ternacle
AU - Guillaume L'Official
AU - Julien Dreyfus
AU - Mohammed Nejjari
AU - Lionel Leroux
AU - Ole de Backer
AU - Azeem Latib
AU - Juan F. Granada
AU - Ralph Stephan von Bardeleben
AU - Thomas Modine
PY - 2026
DA - 2026/10/21
JO - Structural Heart
DO - 10.1016/j.shj.2026.100792
UR - https://hal.science/hal-05830446v1
AB - Severe tricuspid regurgitation remains a major therapeutic challenge, particularly in patients with extensive annular dilation or advanced right heart remodeling. Transcatheter tricuspid valve replacement(TTVR) has emerged as a promising alternative for anatomically complex and high‑risk patients who are not suitable for surgery or transcatheter edge‑to‑edge repair. Among currently available systems, the LuX‑Valve Plus device offers a unique transjugular approach and anchoring strategy. This state‑of‑the‑art review provides a comprehensive overview of the LuX‑Valve Plus system, including technical characteristics, procedural steps, multimodality imaging guidance, and key anatomical considerations for patient selection. Drawing on current literature and expert experience, the review describes a step‑by‑step procedural framework with a focus on anatomical screening, computed tomography-based planning, intraprocedural three‑dimensional transesophageal echocardiography, and the use of advanced imaging modalities such as fusion imaging. Practical tips are provided to optimize device positioning, septal anchoring, and leaflet interaction in the setting of highly variable anatomy. Overall, the LuX‑Valve Plus system broadens the spectrum of TTVR to anatomically challenging patients, and this review offers a practical guide for clinicians by offering detailed technical insights, imaging protocols, and procedural strategies essential for successful implantation and avoidance of complications.
SN - 2474-8706
ER -