Interocular suppression weakens binocular disparity integration in the dorsal visual stream
- 1University of Alabama at Birmingham
Abstract
A unified percept depends on the coordinated interplay of sensory integration and suppression, yet how this interaction is implemented across cortical representations remains unclear. Using binocular vision as a tractable model system, we combined fMRI with multivariate analyses to test how interocular suppression reshapes binocular disparity integration across human visual pathways. Local binocular rivalry weakened near-far disparity decoding, with disruption increasing along the dorsal pathway from V1 to V3A and intraparietal sulcus (IPS), but no reliable loss in ventral regions. In V3A, anticorrelated random-dot stereograms showed an inverted representational relationship relative to correlated stimuli, and this structure was abolished under suppression, indicating disrupted non-canonical disparity integration. Informational connectivity further revealed that suppression selectively weakened V3A-centered coordination while largely sparing coupling among early visual areas. Together, these findings identify higher-level dorsal regions as a key substrate for coordinating integrative and suppressive computations during unified percept formation.
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BibTeX
@misc{jiang2026interocular,
title = {{Interocular suppression weakens binocular disparity integration in the dorsal visual stream}},
author = {R. Jiang and M. Meng},
howpublished = {bioRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.11.751085},
url = {https://www.biorxiv.org/content/10.64898/2026.09.11.751085v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - Interocular suppression weakens binocular disparity integration in the dorsal visual stream
AU - R. Jiang
AU - M. Meng
PY - 2026
DA - 2026/09/11
PB - bioRxiv
DO - 10.64898/2026.09.11.751085
UR - https://www.biorxiv.org/content/10.64898/2026.09.11.751085v1
AB - A unified percept depends on the coordinated interplay of sensory integration and suppression, yet how this interaction is implemented across cortical representations remains unclear. Using binocular vision as a tractable model system, we combined fMRI with multivariate analyses to test how interocular suppression reshapes binocular disparity integration across human visual pathways. Local binocular rivalry weakened near-far disparity decoding, with disruption increasing along the dorsal pathway from V1 to V3A and intraparietal sulcus (IPS), but no reliable loss in ventral regions. In V3A, anticorrelated random-dot stereograms showed an inverted representational relationship relative to correlated stimuli, and this structure was abolished under suppression, indicating disrupted non-canonical disparity integration. Informational connectivity further revealed that suppression selectively weakened V3A-centered coordination while largely sparing coupling among early visual areas. Together, these findings identify higher-level dorsal regions as a key substrate for coordinating integrative and suppressive computations during unified percept formation.
ER -