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Peer-reviewedCC BY-NC-SA 4.0Videosurgery and other Miniinvasive Techniques

Laparoscopic right hemicolectomy for colon cancer: is functional end-to-end anastomosis superior to end-to-side anastomosis? A meta-analysis

  • Feng Chen1
  • Jianxiang Wu1
  • Jianchun Zheng1
  1. 1Emergency Department, Second Hospital of Jiaxing, Jiaxing, Zhejiang Province, China
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Abstract

INTRODUCTION:: Right-sided colon cancer (CC) represents a substantial proportion of colorectal malignancies, and laparoscopic right hemicolectomy has become the established surgical standard of care. However, consensus on the optimal anastomotic configuration—end-to-side vs functional end-to-end—remains lacking in current clinical practice.

AIM:: This study aimed to compare end-to-side anastomosis (ESA) with functional end-to-end anastomosis (FEEA) in laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis, thereby providing evidence-based guidance for selecting the optimal anastomotic technique.

MATERIALS AND METHODS:: We systematically searched PubMed, Web of Science, the Cochrane Library, and Embase for studies comparing ESA with FEEA in laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis. The search included publications up to January 2026 with no language restrictions. Eligible studies were selected based on the population, intervention, comparison, outcome, and study design framework.

RESULTS:: A total of 5 studies were included in the analysis. ESA was associated with a reduced incidence of ileus, as compared with FEEA (P <0.001). No significant differences were observed between ESA and FEEA in length of hospital stay, time to first flatus, overall postoperative complications, anastomotic leakage, postoperative bleeding, or surgical site infection.

CONCLUSIONS:: In laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis, ESA is associated with a lower incidence of ileus than FEEA.

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Cite

BibTeXRIS
BibTeX
@article{chen2026laparoscopic,
  title = {{Laparoscopic right hemicolectomy for colon cancer: is functional end-to-end anastomosis superior to end-to-side anastomosis? A meta-analysis}},
  author = {Feng Chen and Jianxiang Wu and Jianchun Zheng},
  journal = {Videosurgery and other Miniinvasive Techniques},
  year = {2026},
  month = oct,
  doi = {10.20452/wiitm.2026.18053},
  url = {https://doi.org/10.20452/wiitm.2026.18053},
  note = {CC BY-NC-SA 4.0},
}
RIS
TY  - JOUR
TI  - Laparoscopic right hemicolectomy for colon cancer: is functional end-to-end anastomosis superior to end-to-side anastomosis? A meta-analysis
AU  - Feng Chen
AU  - Jianxiang Wu
AU  - Jianchun Zheng
PY  - 2026
DA  - 2026/10/21
JO  - Videosurgery and other Miniinvasive Techniques
DO  - 10.20452/wiitm.2026.18053
UR  - https://doi.org/10.20452/wiitm.2026.18053
AB  - INTRODUCTION:: Right-sided colon cancer (CC) represents a substantial proportion of colorectal malignancies, and laparoscopic right hemicolectomy has become the established surgical standard of care. However, consensus on the optimal anastomotic configuration—end-to-side vs functional end-to-end—remains lacking in current clinical practice.  AIM:: This study aimed to compare end-to-side anastomosis (ESA) with functional end-to-end anastomosis (FEEA) in laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis, thereby providing evidence-based guidance for selecting the optimal anastomotic technique.  MATERIALS AND METHODS:: We systematically searched PubMed, Web of Science, the Cochrane Library, and Embase for studies comparing ESA with FEEA in laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis. The search included publications up to January 2026 with no language restrictions. Eligible studies were selected based on the population, intervention, comparison, outcome, and study design framework.  RESULTS:: A total of 5 studies were included in the analysis. ESA was associated with a reduced incidence of ileus, as compared with FEEA (P <0.001). No significant differences were observed between ESA and FEEA in length of hospital stay, time to first flatus, overall postoperative complications, anastomotic leakage, postoperative bleeding, or surgical site infection.  CONCLUSIONS:: In laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis, ESA is associated with a lower incidence of ileus than FEEA.
SN  - 1895-4588
SN  - 2299-0054
ER  -