Peer-reviewedCC BY-NC-ND 4.0European Journal of Neurology
Cognitive disorders in patients with chronic kidney disease: Approaches to prevention and treatment
Abstract
Cognitive impairment is common in patients with chronic kidney disease (CKD), and early intervention may prevent the progression of this condition. Here, we review interventions for the complications of CKD (anemia, secondary hyperparathyroidism, metabolic acidosis, harmful effects of dialysis, the accumulation of uremic toxins) and for prevention of vascular events, interventions that may potentially be protective against cognitive impairment. Furthermore, we discuss non-pharmacological and pharmacological methods to prevent cognitive impairment and/or minimize the latter's impact on CKD patients' daily lives.
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BibTeX
@article{pepin2026cognitive,
title = {{Cognitive disorders in patients with chronic kidney disease: Approaches to prevention and treatment}},
author = {Marion Pépin and Aleksandra Klimkowicz-Mrowiec and Olivier Godefroy and Pilar Delgado and Sol Carriazo and Ana Carina Ferreira and Aleksandra Golenia and Jolanta Malyszko and Tomasz Grodzicki and Konstantinos Giannakou and Giuseppe Paolisso and Michelangela Barbieri and Liliana Garneata and Carmen Antonia Mocanu and Sophie Liabeuf and Goce Spasovski and Carmine Zoccali and Annette Bruchfeld and Ana Farinha and Mustafa Arici and Giovambattista Capasso and Andrzej Wiecek and Ziad Massy},
journal = {European Journal of Neurology},
year = {2026},
month = oct,
doi = {10.1111/ene.15928},
url = {https://u-picardie.hal.science/hal-04137872v1},
note = {CC BY-NC-ND 4.0},
}
RIS
TY - JOUR
TI - Cognitive disorders in patients with chronic kidney disease: Approaches to prevention and treatment
AU - Marion Pépin
AU - Aleksandra Klimkowicz-Mrowiec
AU - Olivier Godefroy
AU - Pilar Delgado
AU - Sol Carriazo
AU - Ana Carina Ferreira
AU - Aleksandra Golenia
AU - Jolanta Malyszko
AU - Tomasz Grodzicki
AU - Konstantinos Giannakou
AU - Giuseppe Paolisso
AU - Michelangela Barbieri
AU - Liliana Garneata
AU - Carmen Antonia Mocanu
AU - Sophie Liabeuf
AU - Goce Spasovski
AU - Carmine Zoccali
AU - Annette Bruchfeld
AU - Ana Farinha
AU - Mustafa Arici
AU - Giovambattista Capasso
AU - Andrzej Wiecek
AU - Ziad Massy
PY - 2026
DA - 2026/10/14
JO - European Journal of Neurology
DO - 10.1111/ene.15928
UR - https://u-picardie.hal.science/hal-04137872v1
AB - Cognitive impairment is common in patients with chronic kidney disease (CKD), and early intervention may prevent the progression of this condition. Here, we review interventions for the complications of CKD (anemia, secondary hyperparathyroidism, metabolic acidosis, harmful effects of dialysis, the accumulation of uremic toxins) and for prevention of vascular events, interventions that may potentially be protective against cognitive impairment. Furthermore, we discuss non-pharmacological and pharmacological methods to prevent cognitive impairment and/or minimize the latter's impact on CKD patients' daily lives.
SN - 1351-5101
SN - 1468-1331
ER -