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Peer-reviewedCC BY-NC-NDRadiology case reports

Emphysematous pyelonephritis in a diabetic patient: A case report highlighting diagnostic challenges and successful conservative management.

  1. 1Department of Infectious Diseases, The Fifth Clinical Medical College of Henan University of Chinese Medicine, People's Hospital of Zhengzhou, Zhengzhou, China.
  2. 2Department of Emergency, The Fifth Clinical Medical College of Henan University of Chinese Medicine, People's Hospital of Zhengzhou, Zhengzhou, China.

Abstract

Emphysematous pyelonephritis (EPN) is a rare, life-threatening necrotizing renal infection predominantly affecting diabetics. We report a 66-year-old female with uncontrolled type 2 diabetes who presented with right flank pain and fever. CT confirmed Class 2 EPN with gas confined to the renal parenchyma. Blood cultures grew Escherichia coli. She was successfully managed conservatively with imipenem-cilastatin, fluid resuscitation, and insulin therapy, avoiding surgery. This case highlights CT's role in early EPN diagnosis and demonstrates that tailored medical management can be a nephron-sparing alternative in selected patients.

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BibTeX
@article{gao2026emphysematous,
  title = {{Emphysematous pyelonephritis in a diabetic patient: A case report highlighting diagnostic challenges and successful conservative management.}},
  author = {Ya Gao and JianKai Gao},
  journal = {Radiology case reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.radcr.2026.09.055},
  url = {https://europepmc.org/article/MED/42910099},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Emphysematous pyelonephritis in a diabetic patient: A case report highlighting diagnostic challenges and successful conservative management.
AU  - Ya Gao
AU  - JianKai Gao
PY  - 2026
DA  - 2026/10/13
JO  - Radiology case reports
DO  - 10.1016/j.radcr.2026.09.055
UR  - https://europepmc.org/article/MED/42910099
AB  - Emphysematous pyelonephritis (EPN) is a rare, life-threatening necrotizing renal infection predominantly affecting diabetics. We report a 66-year-old female with uncontrolled type 2 diabetes who presented with right flank pain and fever. CT confirmed Class 2 EPN with gas confined to the renal parenchyma. Blood cultures grew Escherichia coli. She was successfully managed conservatively with imipenem-cilastatin, fluid resuscitation, and insulin therapy, avoiding surgery. This case highlights CT's role in early EPN diagnosis and demonstrates that tailored medical management can be a nephron-sparing alternative in selected patients.
SN  - 1930-0433
ER  -