Phlegmonous Gastritis in Chemotherapy-related Neutropenia with Endoscopic Findings that Prompted Early Therapeutic Intervention
Abstract
Phlegmonous gastritis is a rare and potentially fatal infection of the gastric wall that is often difficult to diagnose due to non-specific symptoms. We report the case of a 56-year-old man with chemotherapy-related neutropenia and immunosuppression, who presented with shock and epigastric pain. Computed tomography revealed diffuse gastric wall thickening, and esophagogastroduodenoscopy revealed extensive mucosal injury, prompting the administration of empiric antimicrobial therapy. He responded well to conservative treatment, with clinical and endoscopic improvements. This case underscores that early clinical suspicion based on endoscopic findings combined with timely therapeutic intervention may be lifesaving in immunocompromised patients.
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BibTeX
@article{ota2026phlegmonous,
title = {{Phlegmonous Gastritis in Chemotherapy-related Neutropenia with Endoscopic Findings that Prompted Early Therapeutic Intervention}},
author = {Kazuhiro Ota and Sayaka Tsuji and Masatoshi Kaizuka and Kazuki Takayama and Shun Sasaki and Akitoshi Hakoda and Noriaki Sugawara and Taro Iwatsubo and Yoshitaka Kurisu and Hiroki Nishikawa},
journal = {Internal Medicine},
year = {2026},
month = oct,
doi = {10.2169/internalmedicine.7028-25},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/20/65_7028-25/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Phlegmonous Gastritis in Chemotherapy-related Neutropenia with Endoscopic Findings that Prompted Early Therapeutic Intervention
AU - Kazuhiro Ota
AU - Sayaka Tsuji
AU - Masatoshi Kaizuka
AU - Kazuki Takayama
AU - Shun Sasaki
AU - Akitoshi Hakoda
AU - Noriaki Sugawara
AU - Taro Iwatsubo
AU - Yoshitaka Kurisu
AU - Hiroki Nishikawa
PY - 2026
DA - 2026/10/15
JO - Internal Medicine
DO - 10.2169/internalmedicine.7028-25
UR - https://www.jstage.jst.go.jp/article/internalmedicine/65/20/65_7028-25/_article
AB - Phlegmonous gastritis is a rare and potentially fatal infection of the gastric wall that is often difficult to diagnose due to non-specific symptoms. We report the case of a 56-year-old man with chemotherapy-related neutropenia and immunosuppression, who presented with shock and epigastric pain. Computed tomography revealed diffuse gastric wall thickening, and esophagogastroduodenoscopy revealed extensive mucosal injury, prompting the administration of empiric antimicrobial therapy. He responded well to conservative treatment, with clinical and endoscopic improvements. This case underscores that early clinical suspicion based on endoscopic findings combined with timely therapeutic intervention may be lifesaving in immunocompromised patients.
SN - 1349-7235
SN - 0918-2918
ER -