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Peer-reviewedCC BY-NC-NDBMC anesthesiology

Erector spinae plane block in bariatric surgery: a systematic review and meta-analysis of randomized controlled trials with trial sequence analysis.

5 affiliations
  1. 1Department of Anaesthesiology, Singapore General Hospital, Singapore, Singapore. [email protected].
  2. 2Department of Anaesthesiology, Sengkang General Hospital, Singapore, Singapore. [email protected].
  3. 3Department of Anaesthesiology, Singapore General Hospital, Singapore, Singapore. [email protected].
  4. 4Department of Anaesthesiology, Singapore General Hospital, Singapore, Singapore. [email protected].
  5. 5Department of Anaesthesiology, Singapore General Hospital, Singapore, Singapore. [email protected].

Abstract

Background

The use of erector spinae plane (ESP) block has been reported to decrease opioid requirements for patients undergoing bariatric and metabolic surgeries (BMS). We aim to systematically review and examine the evidence for the use of ESP block in BMS.Methods

MEDLINE, Embase, Scopus, and CENTRAL electronic databases were searched for all studies on ESP block in BMS from database inception through 21st July 2025. Two reviewers independently assessed and selected studies, collected data, assessed the risk of bias and quality of evidence. The primary outcome for this review is opioid consumption in 24 h post-operation. Secondary outcomes include intraoperative opioid consumption, time to first request for analgesia, and postoperative pain scores.Results

Nine randomised control trials involving 613 patients were found to be eligible. ESP block significantly reduced opioid consumption in the first 24 h after surgery, with a mean oral morphine equivalent daily dose (oMMED) reduction of 36.94 mg (95% CI -60.85 to -13.03, p = 0.009, I² = 94%). Trial sequential analysis (TSA) suggests a potential benefit of ESP block though this interpretation is limited by marked statistical heterogeneity. Time to first request for analgesia was significantly prolonged with ESP block. Intraoperative opioid requirements, time to first request for analgesia, and postoperative reported pain scores were reduced in the ESP block group.Conclusions

Current evidence suggests that the bilateral ultrasound-guided ESP block may be a practical technique to improve perioperative pain control and reduce opioid usage in patients undergoing BMS. However, these findings must be interpreted with caution due to the very low to moderate certainty of evidence and high clinical heterogeneity.

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BibTeX
@article{chan2026erector,
  title = {{Erector spinae plane block in bariatric surgery: a systematic review and meta-analysis of randomized controlled trials with trial sequence analysis.}},
  author = {Chi Ho Chan and Wen Jie Mak and Kaiquan Tan and Jacqueline Sim},
  journal = {BMC anesthesiology},
  year = {2026},
  month = aug,
  doi = {10.1186/s12871-026-04130-1},
  url = {https://europepmc.org/article/MED/42972263},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Erector spinae plane block in bariatric surgery: a systematic review and meta-analysis of randomized controlled trials with trial sequence analysis.
AU  - Chi Ho Chan
AU  - Wen Jie Mak
AU  - Kaiquan Tan
AU  - Jacqueline Sim
PY  - 2026
DA  - 2026/08/05
JO  - BMC anesthesiology
DO  - 10.1186/s12871-026-04130-1
UR  - https://europepmc.org/article/MED/42972263
AB  - Background  The use of erector spinae plane (ESP) block has been reported to decrease opioid requirements for patients undergoing bariatric and metabolic surgeries (BMS). We aim to systematically review and examine the evidence for the use of ESP block in BMS.Methods  MEDLINE, Embase, Scopus, and CENTRAL electronic databases were searched for all studies on ESP block in BMS from database inception through 21st July 2025. Two reviewers independently assessed and selected studies, collected data, assessed the risk of bias and quality of evidence. The primary outcome for this review is opioid consumption in 24 h post-operation. Secondary outcomes include intraoperative opioid consumption, time to first request for analgesia, and postoperative pain scores.Results  Nine randomised control trials involving 613 patients were found to be eligible. ESP block significantly reduced opioid consumption in the first 24 h after surgery, with a mean oral morphine equivalent daily dose (oMMED) reduction of 36.94 mg (95% CI -60.85 to -13.03, p = 0.009, I² = 94%). Trial sequential analysis (TSA) suggests a potential benefit of ESP block though this interpretation is limited by marked statistical heterogeneity. Time to first request for analgesia was significantly prolonged with ESP block. Intraoperative opioid requirements, time to first request for analgesia, and postoperative reported pain scores were reduced in the ESP block group.Conclusions  Current evidence suggests that the bilateral ultrasound-guided ESP block may be a practical technique to improve perioperative pain control and reduce opioid usage in patients undergoing BMS. However, these findings must be interpreted with caution due to the very low to moderate certainty of evidence and high clinical heterogeneity.
SN  - 1471-2253
ER  -