Biophysics
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- Viscous mechanical cues encode metastatic behavior through cytoskeletal-nuclear coupling and chromatin remodeling
- Free-Energy and Molecular Dynamics Analysis of Ser195 and Thr195 Rotameric States in Thrombin
- Quantitative fluorescence lifetime imaging of protein microenvironments by genetically encoded compact benzodiazole probes
- Decoding CBM2 binding modes: how similar folds achieve distinct substrate preferences
- Freshwater Blackworms Solving a Maze
- Dual role of the RIG-I 2CARD as a signaling module and a brake on dsRNA translocation
- DiffuChannel: A Conditional Denoising Diffusion Model that Synthesises Single-Molecule Patch-Clamp Data with Exactly Known Idealisation (Ground Truth)
- A chemical perturbation scan on a K2P channel modulator pocket identifies affinity hotspots
- Persistent functionalized triarylmethyl radicals: when spin meets chirality.
- Topology-aware few-shot segmentation improves rice leaf-cell boundary and count fidelity, while correction is risky under tested domain shifts
- Reviewing reproducibility and replicability in 'Deconstructing gastrulation at single-cell resolution' by Stern et al. (2022).
- Distinct extracellular architectures shape mechanical persistence in GPVI and CLEC-2 receptor assemblies
- An Affordable Shifted-Excitation Raman Difference Spectroscopy (SERDS) Setup: Construction, Noise Analysis, and Detection Limits
- Calibrating AlphaFold confidence scores for interface quality
- Distinct activation mechanisms underlie ligand efficacy at a GPCR
- Enhanced DNA Scanning and Target Specificity via Motif Sequestration
- The Signaling Pathway of a Bacterial Two-Component System Determined by cryo-EM
- Understanding the role of chromatin accessibility and compaction on loop extrusion dynamics
- Interlaboratory benchmarking of differential scanning fluorimetry reveals sources of variability in protein thermal stability parameters
- Branching Suppresses Self-Aggregation while Preserving Membrane Association in SET-M33: An Atomistic Molecular Dynamics Study
- Prospective discovery of LasB inhibitors by integrating generative design, free energy ranking, and experimental validation
- GENIE: a multi-agent system for closed-loop autonomous microscopy
- A learning-to-rank framework for large-scale identification of unknown proteins from cryo-EM and cryo-ET maps
- Structural heterogeneity of uncrosslinked FtsH-HflKC assemblies includes variable FtsH occupancy and a distinct wild-type FtsH architecture
- Structural basis for phosphorylation-induced inactivation of the rice ammonium transporter AMT1;1