Molecular biology & gene regulation
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6,626 studies
- Molecular mechanisms of NLR proteins in inflammasome activation
- Spatially resolved host and microbiota RNA profiling in the mouse gut using microDBiT
- Towards scalable DNA data storage with DNA-SaM codec system
- Miro1 mediates skeletal muscle insulin resistance in type 2 diabetes
- Dimeric granzyme-A mediates the specific recognition and cleavage of full-length GSDMB
- Rapid assessment of chemical complementarity of ligands for protein design
- Nuclear adaptation to intracellular mechanical forces regulates the phagocytic capacity of Drosophila macrophages in vivo
- Structure-guided design and dynamic evaluation of VP4-targeting siRNAs against rotavirus A
- DeImmu-MPNN: Reducing Immunogenicity in De Novo Protein Design
- Spin-chemistry modulation of ATP synthesis via vibronic reorganisation
- Martini 3 Coarse-Grained Models for Steroid Hormones
- An artificial macrophage reveals the impact of nitric oxide microenvironments on bacterial viability
- SGK1 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in experimental bronchiolitis obliterans
- Lactate-driven histone lactylation by AARS1 promotes pulmonary arterial hypertension
- Non-invasive glycemic control leveraging ultrasound dose window activation of MscL in diabetic mice
- Notch-dependent left-right asymmetry in β-catenin-TCF activity instructs anteroposterior positioning of motor neurons in the C. elegans ventral nerve cord
- Generative steering to adapt proteins beyond native biological contexts
- Molecular Origins of Catalysis in Random Heteropolymer Enzyme Mimics through All-Atom Simulations
- Harnessing the Ion Transportome to Treat Cancer
- Evolution-Guided Engineering of Non-conserved N-Glycosylation Sites Improves Heterologous Production of Sulfotransferases
- A trans-splicing model for poly(A)-tail addition during VSG mRNA maturation in Trypanosoma brucei
- Recombinant SIRT1 expression and SIRT1 METTL3 interaction analysis with computational identification of phytochemical SIRT1 activators and inhibitors
- Enhanced Fidelity and Sequence Generality of an RNA Polymerase Ribozyme
- Host-Fungus Interactions Link Autoimmune and Immune-Mediated Inflammatory Diseases to Gastrointestinal Cancer: Lessons from KA/KA and Card9-/- Mouse Models.
- Chloride Channels as Determinants of Anti-Cancer Drug Response: Why the Therapeutic Direction Reverses Between Channels and Between Tissues