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Bioinformatics & computational biology

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2,083 studies

  1. Multiplex-GCN Predicts Clinically Actionable Tumor Microenvironment Subtypes in Pancreatic Cancer
    S. Bose, P. B. Upama, S. I. Ahamed
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  2. Neopep: Reinforcement Learning From Machine-Learned Force Field Energy for Non-Canonical Peptide Structure Prediction
    D. Jagannathan, P. M. Kim
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  3. Benchmarking Large Language Models for Transcriptomic Data Analysis and Visualization: Multi-Model Workflow Evaluation
    A. Iyer, A. Subedi, K. S. Butler +1
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  4. Dimensionality Reduction for Cyclic Compositional Data
    Nikhila P. Swarna, Jawhara Emhemed, Lior Pachter
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxivPMC
  5. GLOM TGITO: multiscale protein modelling and multiview landscape-guided sequence discovery
    Y. Xiong, Y. K. Tirta, S. Wang +3
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  6. Asking the Data: Conversational Interrogation of LC-MS/MS Proteomics Data Sets with an LLM Agent
    C. da Silva de Araujo, M. Keirsebelik, A. C. Silas Rodrigues +4
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  7. Best Practices for Pre-Processing Large-Scale ATAC-Seq Data: Why Epidemiological Studies Demand Greater Stringency
    P. M. Wells, M. Flores-Payan, B. Chioza +8
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  8. BenchMHC: a reproducible framework for peptide-MHC presentation prediction
    T. Borck, M. Chabrol, D. Colombo +5
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  9. ProtCell: a foundation model for single-cell proteomics
    B. Hu, Z. Li, Q. Jiang +3
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  10. Metric-driven Pre-acquisition Diagnostics for Automated Microscopy Ultraviolet Surface Excitation (MUSE)
    M. Nunez, B. Davies
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  11. CATFISHR: integration of transcriptome and inferred CNV profiles for comprehensive malignant cell identification
    P. Shukla, M. Mannino, M. Hofer +4
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  12. MPFIL: Multi-Level Protein Feature Integration for Predicting Mutation-Induced Protein-Protein Binding Affinity Changes
    H. Zhang, Y. Liu, L. Yu +1
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  13. CEP-IP with CMRF in SEA-AD Microglia: A Mitochondrial Co-expression Module Linked to Cognition
    Kah Keng Wong
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxivPMC
  14. Characterization of heterogeneous bioinformatics training needs in the AI era
    G. van Geest, V. Di Cola, M. Zahn +7
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  15. An evidence-governed agent harness for spatial transcriptomics prioritizes ICAM-1 as a target in lung fibrosis
    J. Jung, T. Parimon, J. H. Moore +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  16. Mathematical AI Predicts 40% and 57% Influenza Vaccine Effectiveness Against H1N1 and H3N2, Respectively, for the 2026--2027 U.S. Season
    X. X. Wang, G. Wei
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxivPMC
  17. Evaluating the added value of sequence models in noncoding RNA assays: a baseline-aware framework
    R. Guo, W. Shan, R. Liu +3
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  18. Large-scale integrated single-cell analysis reveals molecular subtypes and microenvironmental remodeling in cutaneous T cell lymphoma
    Ryan J Reis, Eric Mou, Vincent Liu +3
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxivPMC
  19. Overcoming segmentation bottlenecks in brain tissue for spatial proteomic inference at population scale
    L. You, J. L. Durbin, G. Meng +6
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxivPMC
  20. AI-guided discovery of natural pocket proteins for portable small-molecule sensing
    L. Huang, Y. Yang, c. Jiang +12
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  21. RiboDFM: Robust RNA sequence design using backbone-conditioned discrete flow matching
    X. Liu, X. An, Z. Peng +2
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  22. Whole-genome sequencing reveals tumor T-cell infiltration associated with immunotherapy outcomes
    J. L. Usset, H. W. Lee, R. Jones +4
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  23. Data mining of global sequence datasets markedly expands known diversity within the Tobamovirus genus
    N. Pajek Arambasic, K. Bacnik, L. Kranjc +3
    bioRxivPreprintCC BYFull text1 citedBioinformatics & computational biologybioRxiv
  24. OmniRE-seq: A Dual-Method Framework for Decoding RNA Editing Dynamics in Disease and Therapy
    Y. Hang, H. Liu, W. Li +3
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  25. Projected Gradient Descent for Hallucination-Based Protein Binder Design
    M. Ross, D. Miller, J. Wells
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv