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Bioinformatics & computational biology

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2,115 studies

  1. Heterogeneous epigenetic regulatory patterns link mammalian aging, development, and mortality
    S. Tikhonov, S. E. Dmitriev
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  2. ImmuneLens: linking transcriptional states and TCR clonotypes through disentangled multimodal learning
    Z. Duan, Y. Wang, C. Li +5
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  3. Isocall enables scalable transcript identification from long-read RNA-sequencing data
    E. Dolzhenko, M. Schertzer, R. Gossart +11
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  4. CIDER: detecting changes in gene regulatory networks that are associated with changes in phenotype
    W. J. Jung, M. Ding, S. Liao +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  5. The Shape of Biological Metadata: Measuring Repository Richness with Entity-Based NLP Metrics
    M. J. Rodriguez-Cubillos, T. Zielinski, J. R. Swedlow +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  6. GPCR Evolution Database
    B. Selcuk, O. Adebali
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  7. PlantLRR-PRR:A Reproducible Annotation Pipeline Reveals Contrasting Evolution of Developmental and Defense Receptor-Like Proteins in Tomato
    N. JALAHALLI RANGEGOWDA, R. Stam
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  8. Unlabeled Echoes: Pseudo-Labels and Genus-Aware Smoothing for Bat Call Recognition
    Frank Fundel, Alexandra Howard
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  9. PHAROS: turning single-cell perturbation models into target-directed drug-combination screens
    J. Bezney, C. Ruggeri, F. Borra +3
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  10. When Metabolism Became Messaging: The Stepwise Evolution of the GABAergic Signaling System
    A. THAKUR, M. Kulharia
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  11. Benchmarking long-read RNA sequencing for de novo transcriptome assembly in non-model plant species: insights from Moricandia arvensis
    S. Sharma, M. Hackenberg, L. Navarro +5
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  12. PhenoMapR: scalable mapping of sample phenotypes to single-cell, spatial, and bulk transcriptomics data
    B. A. Benard, C. K. Lalgudi, A. Azizi +1
    bioRxivPreprintCC BY-NCFull text1 citedBioinformatics & computational biologybioRxiv
  13. TAPAS: Learned integration of AlphaFold3 confidence and geometric features for TCR-pMHC binding prediction
    H. Y. Kim, H. J. Han, D. Kim
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  14. Agent-driven Model Development for RNA 3D Structure Prediction
    M. Majewski, L. Malo, A. Montero-Blay +3
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  15. Protein Design Viz (PDV): lightweight protein structure visualization studio with validated quantitative analytics and antibody-specific toolkit
    K. Krawczyk, P. Dudzic, S. Kumar
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  16. Spatially guided translation from histology images to transcriptomic profiles using foundation model-driven contrastive learning
    Zi Huai Huang, Ziyang Xu, Pingzhao Hu
    PLOS Computational BiologyPeer-reviewedCC BY 4.0Full textBioinformatics & computational biologyPLOS
  17. ForceFlowAb: physics-aware mixture-of-experts flow matching model for antibody CDRs design
    Z. Li, Z. Lv, G. Zhang
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  18. TransBind2: Improving Transcription Factor-DNA Binding Prediction with Multimodal Data and Bidirectional Cross Attention
    S. Basnet, J. Cheng
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  19. HARIBOSS++: An Integrated Platform for RNA-Targeted Drug Design
    M. Marengo, E. Chapeaublanc, H. Menager +2
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  20. Matched full-UDG and non-UDG ancient DNA libraries reveal trade-offs in post-mortem damage correction for imputation and kinship inference
    O. Ravdandorj, C. Sampildondov, K. Janchiv +1
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  21. A Framework for Quantifying DNA Methylation Heterogeneity and Detecting Co-methylated loci from Native Nanopore Sequencing
    Y. J. Kim, N. R. Zabet
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  22. Advancing long-read metagenomic binning via single-copy-gene guided contrastive learning
    H. Han, L. F. Messer, C. Quince +4
    bioRxivPreprintCC BY-NDFull textBioinformatics & computational biologybioRxiv
  23. Independent benchmark of H&E-based gene expression prediction in skin
    R. Shaikhutdinova, S. Gansberger, J. Staller +6
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  24. A Unified Structure-Based Deep-Learning Framework for High-Throughput Screening of Protein-Binding RNAs
    y. zhao, j. han, j. wang +3
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  25. EukaUTR: a foundation model for functional modelling and design of eukaryotic 3' UTRs
    M. lang, X. Fang, M. Chen +6
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv