Bioinformatics & computational biology
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2,115 studies
- A shared functional organisation underlies vascular disease remodelling
- AnnoAudit: a marker-based protocol for auditing single-cell atlas annotations reveals annotation-driven artifacts in a widely used traumatic brain injury resource
- Microhomology-Driven Genomic Alterations in Cancer Genomes: Patterns, Prevalence, and Clinical Implications.
- TCRdenoise - an unsupervised similarity-based approach for denoising of TCR-pMHC specificity data
- A Network-Based Biomarker of Morphological Disruption Associated with Breast Cancer Malignancy
- Real Science Is Harder Than Benchmarks: Evaluating Advanced AI Frameworks on Published Studies. II. Antibody Properties, Lipid-RNA Interactions
- A physics-informed hybrid deep learning model for spatiotemporal rice disease prediction using multi-source data
- Learning from tandem mass spectra at scale with a self-supervised foundation model for proteomics
- A systematic evaluation of SIRT6 as transcriptomic biomarker of aging
- Multiparametric MRI Radiomics and Machine Learning Framework for Predicting Treatment Response in Glioblastoma
- Towards AI-Driven Nanomedicine Discovery: A Benchmark and Multimodal Learning Framework for Nano Self-Assembly Prediction
- When Quantization Breaks Memory: Recurrent-State Write-Back in Low-Precision Temporal Inference
- The Identification of Biological Stains at Crime Scenes: A Promising Role for Proteomics and Machine Learning
- Topological potentials guiding protein self-assembly
- A unified framework for potency-oriented AMP discovery via multi-modal learning and guided sequence synthesis
- High AUROC can mask decision failure in sepsis transcriptomic classifiers: Preprocessing stability outweighs post hoc calibration across cohorts
- OligoSeq: Rapid nanopore-sequencing of single-stranded oligonucleotides
- EvSpark: Lossless Speculative Decoding for Hybrid DNA Foundation Models
- FFPERescuer: deep unsupervised domain adaptation for the reconstruction of gene expression profiles derived from formalin-fixed paraffin-embedded samples
- EISCA and EISTA: Full-Spectrum Pipelines for Single-Cell and Spatial Transcriptomics Analysis
- Predicting Endometriosis Status and Menstrual Cycle Phase Using DNA Methylation
- Benchmark validity in graph neural network scoring of metabolic reaction activity on Recon3D: detecting label leakage, memorized noise and input-invariant models
- WGCNA+: AI-powered WGCNA for Integration of Multi-Omics Data
- Keloid transcriptomics reveal heterogeneity in fibroblast subtype enrichment, gene expression, and immune cell responses
- PharmCast: rapid generation of three-dimensional pharmacophore fingerprints from two-dimensional structure without conformer generation