Bioinformatics & computational biology
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2,115 studies
- SureRoute: Toward a Hallucination-Free Self-Improving Platform for Retrosynthesis
- multiTEMPTED: Joint Dimensionality Reduction of Longitudinal Multi-omic Data with Modality-Specific Temporal Dynamics
- HyperSketch: de Bruijn graph sketching for genomic similarity estimation with Hyperdimensional Computing
- High-throughput genomic feature extraction reveals environmental adaptations of prokaryotes
- Evaluating the Robustness of Path-Preservation Benchmarks for Dimensionality Reduction Across Point-Density Thresholds: Linear and Cyclic Single-Cell Trajectories
- Unlocking Sensitive Data with SPHERE in the Age of AI
- Cooperative Learning with Penalized Linear Mixed-Effects Models for High-Dimensional Clustered Multiview Data
- Turning Domain Expertise into Multi-Dimensional Evaluation of Biomedical AI with Karenina
- Interpretable Multiomics Machine Learning Identifies GSDMB-Associated Epigenetic Repression and Reduced Immune Activity in Metastatic Colorectal Cancer
- VariantFlow: a selective-execution engine for efficient population genomic computation on large variant datasets
- CryoFlex characterizes structural motion between conformations directly from cryo-EM density maps
- Unifying physical and molecular coordinate systems across modalities in spatial biology
- Discovery of novel enzybiotic candidates targeting human bacterial pathogens through large-scale viral-host profiling
- PredIDR3: A new output-encoding scheme and abundant negative source provide more information for deep learning-based protein intrinsic disorder prediction
- Restrictome-EVOLVE: population-resolved haplotype architecture of human antiviral restriction-factor loci
- AnnFlux: object-conditioned neural stochastic differential equations for single-cell perturbation dynamics
- Basophilic Erythroblast Emerges as the Key Turning Point in Polycythemia Vera
- Designing antimicrobials with programmable mechanism and safety
- Model-based evaluation of Targeted-Antibacterial-Plasmids (TAPs) transfer kinetics and resensitization of pOXA-48 carbapenem-resistant Escherichia coli
- Taxonomic classification cost tracks neither sequencing depth nor community richness at single-sample scale: a measured resource protocol for 16S rRNA amplicon pipelines
- A mechanistic modeling framework to interpret ACTH stimulation tests across HPA axis adaptation states and glucocorticoid feedback dynamics
- Operationalizing open-ended biological discovery across single-cell representations
- JUMP-lite: Compact, reproducible benchmarking of cell representations
- EasyBCI Agent: Towards Universal Neural Data Preprocessing for Brain-Computer Interfaces
- Score-Based Generative Data Assimilation for Integrating Aggregated Surveillance Data into Agent-Based Models in Epidemic Tracking