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Bioinformatics & computational biology

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2,083 studies

  1. Deep-Learning Algorithm for Indeterminate Thyroid Nodules: Comparison and Combination with Molecular Testing
    Jichen Yang, Jeffrey Ashton, Jikai Zhang +2
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  2. AcupunctureBench: A Multimodal Benchmark for Evaluating Generative Models in the Acupuncture Domain
    Shusheng Li, Yifei Qu, Zichen Han +12
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  3. AgentCount: An Agentic Workflow for Traceable Colony Counting and Insight Generation from Agar Plate Images
    Zhuosheng Liu, Austin E. Weber
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  4. A System One Approach to General Protein Evolution
    Yibo Wen, Han Liu
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  5. OncoSpot enables benchmarking of cancer spatial transcriptomics methods across tumor evolutionary modes
    P. Bhattarai, W. Yuan, X. M. Zhou +1
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  6. Deterministic DNA-first discovery reveals recurrent genomic architectures
    G. Hu, H. Wang, S. S.-T. Yau
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  7. SQANTI-evidence: isoform-resolved, evidence-tiered structural annotation of unannotated genomes from long-read RNA-seq
    P. Atienza Lopez, A. Conesa
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  8. An end-to-end in silico framework for truth-based validation and regression testing of clinical genome sequencing pipelines, from simulated reads to reportable findings
    B. Dvorsky, M. Komarkova, K. Kollinova +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  9. The Segmentome: a novel representation of the DNA methylome identified by a Bayesian HMM framework
    M. Anvari, N. Torki, M. Mehrmohamadi
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  10. Layer-Specific Source-Anchored Transfer Learning for Multi-Omics Survival Prediction in Younger Breast Cancer Patients
    W. Guo, B. Wang, C. Tatsuoka
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  11. Decoding Cell-type Specific Gene Regulation with CellReg3D by Integrating DNA Large Language Models and 3D Genome Structure
    X. Wang, Y. Zhang, S. Chen +6
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  12. GOParsimony: parsimonious saltation across the Gene Ontology digraph for efficient functional annotation
    P. M. Harrison
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  13. A deep genetic structure phylogenomically frames the closest algal relatives of land plants
    Maaike J. Bierenbroodspot, Cäcilia F. Kunz, Elisa S. Goldbecker +5
    PLOS BiologyPeer-reviewedCC BYFull text5 citedBioinformatics & computational biologyEvolutionary biologyGenetics & genomicsPLOSEurope PMCPMCOpenAlex
  14. Development and cross-cohort evaluation of a multimodal deep-learning model for ER, PR and HER2 status classification in breast cancer
    B. M. Tran, V. A. Nguyen, Q. A. Dang +5
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  15. Sequential syntax of EEG microstates captures the temporal dynamics of inhibitory control
    Omar Cano-Garcia, Keith Guzmán-Díaz, Sergio Rivera-Tello +5
    iSciencePeer-reviewedCC BY 4.0Bioinformatics & computational biologyNeuroscienceCrossrefCell Press
  16. irAEGIS: Pathway-guided interpretable prediction of immune-related adverse events
    A. Budhkar, S. Guo, X. Zhang +2
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  17. Comparative Strategies for Handling Imbalanced QSAR Regression: A Case Study on hERG Activity Prediction
    Ming-Yen Sung, Hsin Liu, Tung-Sheng Cho +2
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  18. Stand-In Effects and Pooling Amplification: Design-Based Tests of Whether Biological World Models Use Actions
    Bowen Xu, Boyu Chen
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  19. Cell lines that share a well are not independent observations in the Tahoe-100M drug screen
    Xuanrui Huang
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  20. Accurate automated photo-identification of Near Eastern and European fire salamanders
    Maayan Yesharim, Hava Goldstein, Gabi Kolodny +7
    arXivPreprintCC BY-SA 4.0Full textBioinformatics & computational biologyarXiv
  21. From Tool State to Scientific Action: Auditing Decision Provenance in Biomedical Research Agents
    Xingyu Yi, Xinya Zhang, Yunshen Zhou +1
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  22. FACET: Feasibility-Automaton Complete Enumeration and Truncation-Free Scoring of Molecular Formulas from MS/MS
    Xujun Che, Depeng Xu, Xiuxia Du
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  23. Can agents reliably design therapeutic antibodies?
    Asli Alpman, Nick Bhattacharya, Aaron Solomon +1
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  24. Governing Equations of Human Sleep Macro-Structure:Symbolic Discovery from 1,106 Nights
    Junhui Gao
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  25. FoXSight: Facilitating Computational Hit Identification in Crystallographic Fragment Screening Experiments
    T. Schulze, A. Meents, M. Rarey +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv