Systems & synthetic biology
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- Three-Dimensional Fluid-Structure Interaction Reveals Trade-offs Among Oxygen Delivery, Shear, and Washout in Pediatric Roller-Pump Cardiopulmonary Bypass
- Growing Macroscopic Functional Human Tissues on 3D Printed Peptide Hydrogels
- High-throughput mapping of kinase-substrate interactions with protein language models and phospho-PCA
- Effects of dose-response relationships on cellular information transmission
- Leukemic fitness predicts treatment-free remission and guides adaptive therapy in chronic myeloid leukemia
- Quanta microscopy enables fluorescence imaging at the native bit-plane rate
- Deep Learning Based Cell Segmentation of 3D Confocal Images of Wood for Enzymatic Hydrolysis Applications
- Single-cell profiling quantifies the dose gap between population-average and complete pY-STAT1/3 suppression by JAK inhibitors
- A multiscale pharmacokinetic-Boolean modelling framework for ibrutinib resistance in a Chronic Lymphocytic Leukaemia case study
- Personalised prediction of anomalous bone regeneration in multiple myeloma patients
- Single-vector AAV delivery of En-ISPmu1 and donor DNA for in vivo targeted genome integration
- Compact CRISPR-based genetic circuitry using a miniature genome-integrated Cas12m protein
- From group-level neurophysiological biomarkers to individual-level phenotyping to identify mechanisms of neurodegenerative disease
- In situ loading of biologics on and tissue redirection of circulating extracellular vesicles with an anchoring nanobody
- Engineered Mycobacterium smegmatis-based intrapleural immunotherapy remodels the pleural immune microenvironment for malignant pleural effusion treatment
- Hydraulic performance of 14-G hemodialysis catheters versus an 8-Fr arterial cannula in a mock 3-kg small-dog cardiopulmonary bypass circuit
- Rapid thermoforming of polycarbonate cell culture accessories from 3D printed molds
- Removal of VirD2 from a synthetic T-DNA complex of Agrobacterium by the host DNA repair protein TDP2
- HelixWings enables AI-driven enzyme engineering for biomimetic cofactor utilization
- Diatom-based treatment of geothermal brines to selectively remove silicon, retain lithium for downstream recovery, and produce omega-3 fatty acids
- An engineered α-1,3-glucanase-derived probe enables sensitive detection of α-1,3-glucan and reveals its soluble release by Aspergillus
- Expanding the galactose oxidase substrate repertoire via a multi-modal computational strategy
- Amino Acid Metabolic Signature Links Pediatric Environmental Enteric Dysfunction to Maternal-Fetal Growth Restriction Across Two Independent Cohorts
- Glutamine-derived NADH fuels lactate production to maximize ATP yield under oxygen consumption constraints in head and neck cancer
- Effect of Clover versus Zipping on Annular Geometry and Dynamics in Tricuspid Edge-to-Edge Repair