Atypical lipomatous tumor of buccal mucosa, misdiagnosis as myxoid lipoma: a case report
5 affiliations
- 1Department of Oral and Maxillofacial Surgery, School of Dentistry, and Department of Head and Neck Oncologic and Reconstructive Surgery, The Cancer Institute, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
- 2School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
- 3Oral and Maxillofacial Pathology Department, School of Dentistry, Tehran University of Medical Sciences, North Amir Abad, Tehran, 1439955934 Iran
- 4Department of Oral and Maxillofacial Surgery, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran
- 5Cancer Preclinical Imaging Group, Preclinical Core Facility, Tehran University of Medical Sciences, Tehran, Iran
Abstract
Background: Atypical lipomatous tumor/well-differentiated liposarcoma is a rare, low-grade, locally aggressive malignant adipocytic neoplasm, particularly uncommon in the head and neck region and oral cavity.
Case presentation: Here, we report a case of atypical lipomatous tumor in a 58-year-old Iranian female presenting with a recurrent submucosal mass on the right buccal mucosa, initially misdiagnosed twice as a myxoid lipoma over a 10-year period.
Conclusions: This case underscores the diagnostic challenges of atypical lipomatous tumor in uncommon sites, such as the buccal mucosa, highlighting the importance of awareness about variable microscopic features of this rare neoplasm to prevent misdiagnosis and also it`s uncommon aggressive behavior despite low-grade nature. We emphasize early and accurate diagnosis of this tumor and long-term follow-up of the patient maybe inhibit late-stage complications.
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BibTeX
@article{garajei2026atypical,
title = {{Atypical lipomatous tumor of buccal mucosa, misdiagnosis as myxoid lipoma: a case report}},
author = {Ata Garajei and Matin Abdoos and Monir Moradzadeh Khiavi and Arman Sohrabi Seresht and Samira Derakhshan},
journal = {Journal of Medical Case Reports},
year = {2026},
month = aug,
doi = {10.1186/s13256-026-06128-2},
url = {https://doi.org/10.1186/s13256-026-06128-2},
note = {CC BY-NC-ND 4.0},
}
RIS
TY - JOUR
TI - Atypical lipomatous tumor of buccal mucosa, misdiagnosis as myxoid lipoma: a case report
AU - Ata Garajei
AU - Matin Abdoos
AU - Monir Moradzadeh Khiavi
AU - Arman Sohrabi Seresht
AU - Samira Derakhshan
PY - 2026
DA - 2026/08/06
JO - Journal of Medical Case Reports
DO - 10.1186/s13256-026-06128-2
UR - https://doi.org/10.1186/s13256-026-06128-2
AB - Background: Atypical lipomatous tumor/well-differentiated liposarcoma is a rare, low-grade, locally aggressive malignant adipocytic neoplasm, particularly uncommon in the head and neck region and oral cavity. Case presentation: Here, we report a case of atypical lipomatous tumor in a 58-year-old Iranian female presenting with a recurrent submucosal mass on the right buccal mucosa, initially misdiagnosed twice as a myxoid lipoma over a 10-year period. Conclusions: This case underscores the diagnostic challenges of atypical lipomatous tumor in uncommon sites, such as the buccal mucosa, highlighting the importance of awareness about variable microscopic features of this rare neoplasm to prevent misdiagnosis and also it`s uncommon aggressive behavior despite low-grade nature. We emphasize early and accurate diagnosis of this tumor and long-term follow-up of the patient maybe inhibit late-stage complications.
SN - 1752-1947
ER -