Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report

Abstract

A 56-year-old man with chronic progressive pulmonary aspergillosis due to multidrug-resistant Aspergillus udagawae presented with acute abdominal pain. Computed tomography revealed rupture of an intra-abdominal abscess with ascites. Despite emergency surgery for peritonitis, he died on day 5. Autopsy showed numerous fungal abscesses with direct invasion and hematogenous spread from the lungs to the peritoneum. A genetic analysis confirmed A. udagawae. This represents the first autopsy-proven case of fatal fungal peritonitis secondary to invasive pulmonary aspergillosis caused by A. udagawae, highlighting the importance of molecular identification in treatment-refractory Aspergillus infections.

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BibTeX RIS

BibTeX

@article{nishino2026fatal,
  title = {{Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report}},
  author = {Kengo Nishino and Takumi Kiwamoto and Chio Sakai and Natsumi Kawamatsu and Takahiro Takeishi and Kenya Kuramoto and Kazufumi Yoshida and Yusuke Ohara and Chikako Tsurushige and Katsuhiko Kamei and Nobuyuki Hizawa},
  journal = {Internal Medicine},
  year = {2026},
  month = sep,
  doi = {10.2169/internalmedicine.6744-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6744-25/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report
AU  - Kengo Nishino
AU  - Takumi Kiwamoto
AU  - Chio Sakai
AU  - Natsumi Kawamatsu
AU  - Takahiro Takeishi
AU  - Kenya Kuramoto
AU  - Kazufumi Yoshida
AU  - Yusuke Ohara
AU  - Chikako Tsurushige
AU  - Katsuhiko Kamei
AU  - Nobuyuki Hizawa
PY  - 2026
DA  - 2026/09/15
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6744-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6744-25/_article
AB  - A 56-year-old man with chronic progressive pulmonary aspergillosis due to multidrug-resistant Aspergillus udagawae presented with acute abdominal pain. Computed tomography revealed rupture of an intra-abdominal abscess with ascites. Despite emergency surgery for peritonitis, he died on day 5. Autopsy showed numerous fungal abscesses with direct invasion and hematogenous spread from the lungs to the peritoneum. A genetic analysis confirmed A. udagawae. This represents the first autopsy-proven case of fatal fungal peritonitis secondary to invasive pulmonary aspergillosis caused by A. udagawae, highlighting the importance of molecular identification in treatment-refractory Aspergillus infections.
SN  - 1349-7235
SN  - 0918-2918
ER  -

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