Perioperative Spinal Cord Stimulation Combined With Targeted Muscle Reinnervation for Chronic Neuropathic Pain: A Case Report.
- 1Department of Anesthesiology, Rush University Medical Center, Chicago, USA.
- 2Department of Plastic Surgery, Rush University Medical Center, Chicago, USA.
Abstract
Phantom limb pain (PLP) and residual limb pain (RLP) are often difficult to treat with pharmacologic regimen alone and affect many lower extremity amputation patients. We report the case of a 56-year-old female patient with chronic PLP and a right above-the-knee amputation who underwent perioperative spinal cord stimulation (SCS) in conjunction with targeted nerve reinnervation. Following SCS implantation and surgical intervention, the patient reported sustained significant pain reduction of approximately 80% over three months, improved function, and cessation of analgesic use. This case illustrates the feasibility of sequential central neuromodulation and peripheral nerve reconstruction in refractory post-amputation pain and generates the hypothesis that these approaches may have complementary roles.
Related
- Long-term effects of spinal cord stimulation combined with a physiotherapist-led exercise programme and physical activity on prescription for chronic neuropathic pain.
- Targeted muscle reinnervation after traumatic or elective upper-extremity amputation: a systematic review and meta-analysis
- Real-world device survival, revision burden and observed pain patterns after epidural spinal cord stimulation for neuropathic pain in adults with spinal cord injury: protocol for a longitudinal observational cohort study using routine clinical data
- Distinguishing clinical efficacy from vagal target engagement in perioperative transcutaneous auricular vagus nerve stimulation.
- Mechanical Compression-Induced Peripheral Neuropathic Pain: From Astrocyte Mechanosensing and Phenotypic Reprogramming to CCL2-CCR2 Axis-Targeted Therapies.
BibTeX
@article{suvar2026perioperative,
title = {{Perioperative Spinal Cord Stimulation Combined With Targeted Muscle Reinnervation for Chronic Neuropathic Pain: A Case Report.}},
author = {Tolga Suvar and Angie Jung and Robert J McCarthy and David Kurlander},
journal = {Cureus},
year = {2026},
month = sep,
doi = {10.7759/cureus.116867},
url = {https://europepmc.org/article/MED/42927392},
note = {CC BY},
}
RIS
TY - JOUR
TI - Perioperative Spinal Cord Stimulation Combined With Targeted Muscle Reinnervation for Chronic Neuropathic Pain: A Case Report.
AU - Tolga Suvar
AU - Angie Jung
AU - Robert J McCarthy
AU - David Kurlander
PY - 2026
DA - 2026/09/24
JO - Cureus
DO - 10.7759/cureus.116867
UR - https://europepmc.org/article/MED/42927392
AB - Phantom limb pain (PLP) and residual limb pain (RLP) are often difficult to treat with pharmacologic regimen alone and affect many lower extremity amputation patients. We report the case of a 56-year-old female patient with chronic PLP and a right above-the-knee amputation who underwent perioperative spinal cord stimulation (SCS) in conjunction with targeted nerve reinnervation. Following SCS implantation and surgical intervention, the patient reported sustained significant pain reduction of approximately 80% over three months, improved function, and cessation of analgesic use. This case illustrates the feasibility of sequential central neuromodulation and peripheral nerve reconstruction in refractory post-amputation pain and generates the hypothesis that these approaches may have complementary roles.
SN - 2168-8184
ER -