Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 11 min ago
Peer-reviewedCC BY-NC 4.0International Wound Journal

Clinical Outcomes of Patients Hospitalized With Diabetic Foot Ulcer at a Tertiary Hospital in Ethiopia: A 5‐Year Retrospective Audit

  • Melaku Taye Amogne1
  • Feven Moges Gorfe2
  • Karenzi Irenee David3
  • Ahmed Reja1
  1. 1Department of Internal Medicine, College of Health Sciences Addis Ababa University Addis Ababa Ethiopia
  2. 2MCM Comprehensive Specialized Hospital Addis Ababa Ethiopia
  3. 3King Faisal Hospital Rwanda Kigali Rwanda
Read full textPDFDOICite

Abstract

Diabetic foot ulcer is a major cause of hospitalization and lower extremity amputation, particularly in low‐resource settings where patients frequently present with advanced wound. This study assessed the clinical outcomes of patients admitted with diabetic foot ulcer. We conducted a retrospective study of patients admitted to a public hospital in Ethiopia with diabetic foot ulcer. The primary outcome was lower‐extremity amputation. Descriptive analyses, bivariate comparisons, and logistic regression were performed. A total of 146 patients hospitalized with diabetic foot ulcer were included. The mean (±SD) age was 59.4 (±11.7) years. Most patients presented with advanced disease: 86.3% had Wagner grade ≥ 3% and 60.3% had Texas stage C/D. Overall, 53.4% underwent lower‐extremity amputation. Factors associated with higher odds of amputation were: long standing diabetes (duration ≥ 10 years: Adjusted Odds Ratio: 2.42; [95% Confidence Interval: 1.01–5.80]), longer ulcer duration (every day of delayed presentation: 1.02 [1.01–1.03]), previous foot ulcer (4.34 [1.55–12.13]), advanced ulcer stages with University of Texas stage C or D (2.86 [1.19–6.90]). Hospitalized diabetic foot ulcer patients presented with advanced disease and experienced a very high lower‐extremity amputation burden. This high in‐hospital amputation rate in a low‐income country highlights the profound disparity in preventive and limb‐saving diabetic foot interventions.

Related

  1. Epidemiology, Clinical Profiles, Antimicrobial Resistance, and Inflammatory Risk Factors of Aeromonas Infections in Hospitalized Patients: A Retrospective Cohort Study from a Hospital in Zhoushan Archipelago, China
    Yuechuan Shen, Hui He, Ziyun Lin +4
    Infection and Drug ResistancePeer-reviewedCC BY-NC 4.0Full textGeneral medicinePMC
  2. Association between nursing assessment indicators and adverse outcomes in hospitalized patients with atrial fibrillation : A retrospective observational study
    Jie Han, Siyu Liu, Nan Li +1
    MedicinePeer-reviewedCC BYFull textGeneral medicineEurope PMCPMC
  3. Clinical Outcomes of Topical Recombinant Human Epidermal Growth Factor in Diabetic Foot Ulcers: A Retrospective Single-Centre Cohort Study.
    Haci Vural Soyer, Sinan Aslan, Samed Sayar +1
    International wound journalPeer-reviewedCC BY-NCFull textEndocrinology & metabolismEurope PMC
  4. Clinical Manifestations and Outcomes of Hospitalized Patients With Blastomycosis: A Provincial Cohort Study.
    Benjamin Meyers, John Embil, Robert Balshaw +9
    Open forum infectious diseasesPeer-reviewedCC BY-NC-NDFull textEpidemiology & public healthEurope PMC
  5. In-Hospital Guideline-Directed Medical Therapy Intensification and Long-Term Outcomes in Patients Hospitalized for Heart Failure in the Current Clinical Paradigm ― Insights From the QHEART-R Study ―
    Toru Hashimoto, Ryuichi Matsukawa, Shouji Matsushima +15
    Circulation JournalPeer-reviewedCC BY-NC-NDFull textCardiovascular medicineJ-STAGE

Cite

BibTeXRIS
BibTeX
@article{amogne2026clinical,
  title = {{Clinical Outcomes of Patients Hospitalized With Diabetic Foot Ulcer at a Tertiary Hospital in Ethiopia: A 5‐Year Retrospective Audit}},
  author = {Melaku Taye Amogne and Feven Moges Gorfe and Karenzi Irenee David and Ahmed Reja},
  journal = {International Wound Journal},
  year = {2026},
  month = oct,
  doi = {10.1111/iwj.71086},
  url = {https://doi.org/10.1111/iwj.71086},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - Clinical Outcomes of Patients Hospitalized With Diabetic Foot Ulcer at a Tertiary Hospital in Ethiopia: A 5‐Year Retrospective Audit
AU  - Melaku Taye Amogne
AU  - Feven Moges Gorfe
AU  - Karenzi Irenee David
AU  - Ahmed Reja
PY  - 2026
DA  - 2026/10/01
JO  - International Wound Journal
DO  - 10.1111/iwj.71086
UR  - https://doi.org/10.1111/iwj.71086
AB  - Diabetic foot ulcer is a major cause of hospitalization and lower extremity amputation, particularly in low‐resource settings where patients frequently present with advanced wound. This study assessed the clinical outcomes of patients admitted with diabetic foot ulcer. We conducted a retrospective study of patients admitted to a public hospital in Ethiopia with diabetic foot ulcer. The primary outcome was lower‐extremity amputation. Descriptive analyses, bivariate comparisons, and logistic regression were performed. A total of 146 patients hospitalized with diabetic foot ulcer were included. The mean (±SD) age was 59.4 (±11.7) years. Most patients presented with advanced disease: 86.3% had Wagner grade ≥ 3% and 60.3% had Texas stage C/D. Overall, 53.4% underwent lower‐extremity amputation. Factors associated with higher odds of amputation were: long standing diabetes (duration ≥ 10 years: Adjusted Odds Ratio: 2.42; [95% Confidence Interval: 1.01–5.80]), longer ulcer duration (every day of delayed presentation: 1.02 [1.01–1.03]), previous foot ulcer (4.34 [1.55–12.13]), advanced ulcer stages with University of Texas stage C or D (2.86 [1.19–6.90]). Hospitalized diabetic foot ulcer patients presented with advanced disease and experienced a very high lower‐extremity amputation burden. This high in‐hospital amputation rate in a low‐income country highlights the profound disparity in preventive and limb‐saving diabetic foot interventions.
SN  - 1742-4801
SN  - 1742-481X
ER  -