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PreprintCC BYChemRxiv

Use of Gas Chromatography, Nuclear Magnetic Resonance and Fluorescent methods to Estimate Enantiomeric Excess in Asymmetric Transfer Hydrogenation.

  • Michael Chu
  • Shiyun Chen
  • Thomas H. Hall
  • Roy Hodgkinson
  • David Robson
  • Robert Messias
  • Shweta K. Gediya
  • Tasbiha Khan
  • Noha Khamis
  • Martin Wills
Open at sourceDOICite

Abstract

The use of Gas Chromatography, Nuclear Magnetic Resonance and fluorescent methods to estimate ee are described, using asymmetric transfer hydrogenation (ATH) of acetophenone derivatives as a platform for the methodology. The use of rapid analysis processes may facilitate the screening samples through a simple process without having to use chiral HPLC or GC when generating an approximation of enantioselectivity.

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Cite

BibTeXRIS
BibTeX
@misc{chu2026chromatography,
  title = {{Use of Gas Chromatography, Nuclear Magnetic Resonance and Fluorescent methods to Estimate Enantiomeric Excess in Asymmetric Transfer Hydrogenation.}},
  author = {Michael Chu and Shiyun Chen and Thomas H. Hall and Roy Hodgkinson and David Robson and Robert Messias and Shweta K. Gediya and Tasbiha Khan and Noha Khamis and Martin Wills},
  howpublished = {ChemRxiv},
  year = {2026},
  month = sep,
  doi = {10.26434/chemrxiv.15008873/v1},
  url = {https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008873/v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - Use of Gas Chromatography, Nuclear Magnetic Resonance and Fluorescent methods to Estimate Enantiomeric Excess in Asymmetric Transfer Hydrogenation.
AU  - Michael Chu
AU  - Shiyun Chen
AU  - Thomas H. Hall
AU  - Roy Hodgkinson
AU  - David Robson
AU  - Robert Messias
AU  - Shweta K. Gediya
AU  - Tasbiha Khan
AU  - Noha Khamis
AU  - Martin Wills
PY  - 2026
DA  - 2026/09/15
PB  - ChemRxiv
DO  - 10.26434/chemrxiv.15008873/v1
UR  - https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008873/v1
AB  - The use of Gas Chromatography, Nuclear Magnetic Resonance and fluorescent methods to estimate ee are described, using asymmetric transfer hydrogenation (ATH) of acetophenone derivatives as a platform for the methodology. The use of rapid analysis processes may facilitate the screening samples through a simple process without having to use chiral HPLC or GC when generating an approximation of enantioselectivity.
ER  -