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Peer-reviewedCC BYThe American journal of tropical medicine and hygiene

Case of Bundibugyo Virus Disease in Goma, Democratic Republic of the Congo with Lack of Transmission to Breastfeeding Infant.

  • Felicien M Maisha1,2,3
  • Kahatwa K Serge1,4
  • Kambale Kasonia5,6
  • Zebedée Luhavo Kakule1
  • Jayakrishnan Ajayakumar7
  • John A Lednicky3,8
  • Andrew J Curtis7
  • J Glenn Morris3
8 affiliations
  1. 1HEAL Africa Hospital, Goma, Democratic Republic of the Congo.
  2. 2Department of Sociology, University of Goma, Goma, Democratic Republic of the Congo.
  3. 3Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.
  4. 4Department of Internal Medicine, University of Goma, Goma, Democratic Republic of the Congo.
  5. 5Department of Internal Medicine, Universite Libre des Pays de Grands Lacs, Goma, Democratic Republic of the Congo.
  6. 6Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
  7. 7Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  8. 8Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA.
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Abstract

Disease due to Bundibugyo virus (BDBV), an Orthoebolavirus species, reemerged in April 2026, in Ituri Province, Democratic Republic of the Congo. A 35-year-old woman transported the body of a possible BDBV-infected patient from Bunia in Ituri Province to Goma for burial; she was accompanied by an 8-month-old breastfeeding child. Six days after arrival in Goma, she noted onset of fever and malaise and was empirically started on therapy for malaria; 4 days later she developed bloody diarrhea and a bloody vaginal discharge and was started on metronidazole for possible amebic dysentery. When her condition worsened she was admitted to hospital in Goma, where a blood sample was positive by real-time polymerase chain reaction (RT-PCR) test for BDBV, with a second positive test on hospital day 7. By day 14 of hospitalization fever and major symptoms had resolved and repeat RT-PCR tests × 2 were negative. Her child did not show evidence of infection, and no family members or health care workers at HEAL Africa Hospital developed illness.

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Cite

BibTeXRIS
BibTeX
@article{maisha2026case,
  title = {{Case of Bundibugyo Virus Disease in Goma, Democratic Republic of the Congo with Lack of Transmission to Breastfeeding Infant.}},
  author = {Felicien M Maisha and Kahatwa K Serge and Kambale Kasonia and Zebedée Luhavo Kakule and Jayakrishnan Ajayakumar and John A Lednicky and Andrew J Curtis and J Glenn Morris},
  journal = {The American journal of tropical medicine and hygiene},
  year = {2026},
  month = oct,
  doi = {10.4269/ajtmh.26-0480},
  url = {https://europepmc.org/article/MED/42869002},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Case of Bundibugyo Virus Disease in Goma, Democratic Republic of the Congo with Lack of Transmission to Breastfeeding Infant.
AU  - Felicien M Maisha
AU  - Kahatwa K Serge
AU  - Kambale Kasonia
AU  - Zebedée Luhavo Kakule
AU  - Jayakrishnan Ajayakumar
AU  - John A Lednicky
AU  - Andrew J Curtis
AU  - J Glenn Morris
PY  - 2026
DA  - 2026/10/13
JO  - The American journal of tropical medicine and hygiene
DO  - 10.4269/ajtmh.26-0480
UR  - https://europepmc.org/article/MED/42869002
AB  - Disease due to Bundibugyo virus (BDBV), an Orthoebolavirus species, reemerged in April 2026, in Ituri Province, Democratic Republic of the Congo. A 35-year-old woman transported the body of a possible BDBV-infected patient from Bunia in Ituri Province to Goma for burial; she was accompanied by an 8-month-old breastfeeding child. Six days after arrival in Goma, she noted onset of fever and malaise and was empirically started on therapy for malaria; 4 days later she developed bloody diarrhea and a bloody vaginal discharge and was started on metronidazole for possible amebic dysentery. When her condition worsened she was admitted to hospital in Goma, where a blood sample was positive by real-time polymerase chain reaction (RT-PCR) test for BDBV, with a second positive test on hospital day 7. By day 14 of hospitalization fever and major symptoms had resolved and repeat RT-PCR tests × 2 were negative. Her child did not show evidence of infection, and no family members or health care workers at HEAL Africa Hospital developed illness.
SN  - 0002-9637
SN  - 1476-1645
ER  -