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PreprintCC BY 4.0arXiv

Complementary-Aperture Pulse Sequencing for Fundamental-Band Nonlinearity Parameter Imaging

Abstract

The depletion method (DM) enables the estimation of the acoustic nonlinearity parameter, B/A, in pulse-echo ultrasound using fundamental-band signals from low- and high-pressure acquisitions, but requires accurate knowledge of the acoustic-pressure scaling factor. This requirement limits experimental translation because of the slightly nonlinear scaling between excitation voltage set on the ultrasound system and pressure at the probe. We propose a complementary-aperture pulse sequence (CAPS) that recovers the linearly scaled low-pressure signal by coherently summing RF acquisitions from interleaved transmit subapertures whereas a full-aperture transmission provides the high-pressure signal maintaining the same excitation voltage configured in the ultrasound system. In silico phantoms of a homogeneous sample and a reference evaluated four aperture partitions of CAPS and compared them with the DM under relative scaling-factor errors from 0.01% to 10%. Using the DM, errors of 0.1% and 1% produced absolute B/A biases of up to 27.3% and 58.3%, respectively. CAPS yielded mean B/A values of 8.9 for a prescribed value of 9, with biases of less than 1.3% across all partitions, matching an ideally calibrated DM. These results demonstrate that CAPS preserves depletion-based B/A estimation without using the pressure scaling factor as a reconstruction input, supporting experimental and in vivo implementation without pressure-ratio calibration.

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BibTeX
@misc{aviles2026complementaryaperture,
  title = {{Complementary-Aperture Pulse Sequencing for Fundamental-Band Nonlinearity Parameter Imaging}},
  author = {Esteban Avilés and Michael Oelze and Roberto Lavarello and Andres Coila},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.23155},
  eprint = {2609.23155},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2609.23155},
  note = {CC BY 4.0},
}
RIS
TY  - UNPB
TI  - Complementary-Aperture Pulse Sequencing for Fundamental-Band Nonlinearity Parameter Imaging
AU  - Esteban Avilés
AU  - Michael Oelze
AU  - Roberto Lavarello
AU  - Andres Coila
PY  - 2026
DA  - 2026/09/19
PB  - arXiv
DO  - 10.48550/arxiv.2609.23155
UR  - https://arxiv.org/abs/2609.23155
AB  - The depletion method (DM) enables the estimation of the acoustic nonlinearity parameter, B/A, in pulse-echo ultrasound using fundamental-band signals from low- and high-pressure acquisitions, but requires accurate knowledge of the acoustic-pressure scaling factor. This requirement limits experimental translation because of the slightly nonlinear scaling between excitation voltage set on the ultrasound system and pressure at the probe. We propose a complementary-aperture pulse sequence (CAPS) that recovers the linearly scaled low-pressure signal by coherently summing RF acquisitions from interleaved transmit subapertures whereas a full-aperture transmission provides the high-pressure signal maintaining the same excitation voltage configured in the ultrasound system. In silico phantoms of a homogeneous sample and a reference evaluated four aperture partitions of CAPS and compared them with the DM under relative scaling-factor errors from 0.01% to 10%. Using the DM, errors of 0.1% and 1% produced absolute B/A biases of up to 27.3% and 58.3%, respectively. CAPS yielded mean B/A values of 8.9 for a prescribed value of 9, with biases of less than 1.3% across all partitions, matching an ideally calibrated DM. These results demonstrate that CAPS preserves depletion-based B/A estimation without using the pressure scaling factor as a reconstruction input, supporting experimental and in vivo implementation without pressure-ratio calibration.
ER  -