Myocardial Perfusion and Fluorodeoxyglucose Uptake Patterns in Cardiac Sarcoidosis Stratified by Diagnostic…

Abstract

BACKGROUND: F-FDG PET/CT patterns in cardiac sarcoidosis (CS) across diagnostic subgroups are incompletely characterized. METHODS AND RESULTS: We analyzed 221 patients with definite CS (DCS), probable CS with active extracardiac sarcoidosis (PCS-A), or probable CS without extracardiac involvement (PCS-N). DCS exhibited more severe perfusion defects than PCS-A and PCS-N. FDG uptake was similar in DCS and PCS-A, but lower in PCS-N. Abnormalities predominated in the basal/mid-septum and apical cap. CONCLUSIONS: Distinct PET patterns characterize CS diagnostic categories and support current diagnostic criteria.

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BibTeX

@article{sykora2026myocardial,
  title = {{Myocardial Perfusion and Fluorodeoxyglucose Uptake Patterns in Cardiac Sarcoidosis Stratified by Diagnostic Category and Systemic Involvement}},
  author = {Daniel Sykora and Jen Davison and Gregorio Tersalvi and Mohamed Elwazir and Omar AbouEzzeddine and John Bois and John Giudicessi and Panithaya Chareonthaitawee and Leslie Cooper and Andrew Rosenbaum},
  journal = {Circulation Journal},
  year = {2026},
  month = oct,
  doi = {10.1253/circj.cj-26-0423},
  url = {https://www.jstage.jst.go.jp/article/circj/90/11/90_CJ-26-0423/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Myocardial Perfusion and Fluorodeoxyglucose Uptake Patterns in Cardiac Sarcoidosis Stratified by Diagnostic Category and Systemic Involvement
AU  - Daniel Sykora
AU  - Jen Davison
AU  - Gregorio Tersalvi
AU  - Mohamed Elwazir
AU  - Omar AbouEzzeddine
AU  - John Bois
AU  - John Giudicessi
AU  - Panithaya Chareonthaitawee
AU  - Leslie Cooper
AU  - Andrew Rosenbaum
PY  - 2026
DA  - 2026/10/23
JO  - Circulation Journal
DO  - 10.1253/circj.cj-26-0423
UR  - https://www.jstage.jst.go.jp/article/circj/90/11/90_CJ-26-0423/_article
AB  - BACKGROUND: F-FDG PET/CT patterns in cardiac sarcoidosis (CS) across diagnostic subgroups are incompletely characterized. METHODS AND RESULTS: We analyzed 221 patients with definite CS (DCS), probable CS with active extracardiac sarcoidosis (PCS-A), or probable CS without extracardiac involvement (PCS-N). DCS exhibited more severe perfusion defects than PCS-A and PCS-N. FDG uptake was similar in DCS and PCS-A, but lower in PCS-N. Abnormalities predominated in the basal/mid-septum and apical cap. CONCLUSIONS: Distinct PET patterns characterize CS diagnostic categories and support current diagnostic criteria.
SN  - 1347-4820
SN  - 1346-9843
ER  -

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