Endoscopic endonasal management of giant pediatric craniopharyngioma
8 affiliations
- 1Department of Otolaryngology, Rady Children’s Hospital, San Diego
- 2Department of Head and Neck Surgery, Kaiser Permanente Orange County, Anaheim, California
- 3Department of Otolaryngology, Mayo Clinic, Rochester, Minnesota
- 4Department of Otolaryngology, Naval Medical Center San Diego
- 5Department of Neurosurgery, University of California, San Diego
- 6Department of Pediatrics, University of California, Irvine
- 7Department of Neurology, University of California, Irvine; and
- 8Department of Neurosurgery, Rady Children’s Hospital, San Diego, California
Abstract
A 13-year-old girl with growth deceleration and multiple endocrinopathies was found to have a giant adamantinomatous craniopharyngioma with hydrocephalus. She underwent an endoscopic endonasal approach with gross-total resection of the tumor with preservation of the hypothalamus. Postoperatively she developed expected panhypopituitarism given pituitary stalk involvement but had no neurological deficits. On 3-year follow-up, there was no tumor recurrence, hypothalamic dysfunction, or hydrocephalus. Pediatric craniopharyngioma remains challenging to manage given complex patterns of spread and proximity to critical neurovascular structures. Advancements in endoscopic techniques have allowed for dynamic visualization and excellent suprasellar access with high cure rates and low morbidity.
The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID2656
Related
- Management of a giant pediatric craniopharyngioma: staged endoscopic endonasal and cranial approaches
- Staged endoscopic endonasal and bifrontal interhemispheric resection of a giant craniopharyngioma: a two-corridor maximal safe resection strategy
- Endoscopic endonasal transcavernous posterior clinoidectomy with pituitary transposition for resection of a craniopharyngioma
- Endoscopic endonasal transtuberculum-transplanum-translamina terminalis approach for third ventricle craniopharyngioma: 2D operative video
- Multicompartmental hypothalamic craniopharyngioma resection via expanded endonasal endoscopic transplanum-transtuberculum approach.
BibTeX
@article{cheng2026endoscopic,
title = {{Endoscopic endonasal management of giant pediatric craniopharyngioma}},
author = {Michael Z. Cheng and Bastien A. Valencia and Jeeho D. Kim and Michael G. Brandel and John R. Crawford and Jillian Plonsker and Vijay A. Patel and Michael L. Levy},
journal = {Neurosurgical Focus: Video},
year = {2026},
month = oct,
doi = {10.3171/2026.7.focvid2656},
url = {https://doi.org/10.3171/2026.7.focvid2656},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Endoscopic endonasal management of giant pediatric craniopharyngioma
AU - Michael Z. Cheng
AU - Bastien A. Valencia
AU - Jeeho D. Kim
AU - Michael G. Brandel
AU - John R. Crawford
AU - Jillian Plonsker
AU - Vijay A. Patel
AU - Michael L. Levy
PY - 2026
DA - 2026/10/01
JO - Neurosurgical Focus: Video
DO - 10.3171/2026.7.focvid2656
UR - https://doi.org/10.3171/2026.7.focvid2656
AB - A 13-year-old girl with growth deceleration and multiple endocrinopathies was found to have a giant adamantinomatous craniopharyngioma with hydrocephalus. She underwent an endoscopic endonasal approach with gross-total resection of the tumor with preservation of the hypothalamus. Postoperatively she developed expected panhypopituitarism given pituitary stalk involvement but had no neurological deficits. On 3-year follow-up, there was no tumor recurrence, hypothalamic dysfunction, or hydrocephalus. Pediatric craniopharyngioma remains challenging to manage given complex patterns of spread and proximity to critical neurovascular structures. Advancements in endoscopic techniques have allowed for dynamic visualization and excellent suprasellar access with high cure rates and low morbidity. The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID2656
SN - 2643-5217
ER -