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Peer-reviewedCC BYBrazilian oral research

Association between demarcated opacities in primary canines and hypomineralized second primary molars

  • Mylenne Karolayne Silva Ribeiro1
  • Lavínia Lourenço Costa1
  • Luisa Madeira Lemos1
  • Jaderson Felipe Santos Dantas1
  • Patrícia Bittencourt Santos2
  1. 1Universidade Federal do Rio Grande do Norte – UFRN, Graduate Program in Dental Sciences, Department of Dentistry, Natal, RN, Brazil.
  2. 2Universidade Federal do Rio Grande do Norte – UFRN, Department of Dentistry, Natal, RN, Brazil.
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Abstract

To evaluate the association between the presence of demarcated opacities in primary canines and the occurrence of hypomineralized second primary molars (HSPM) in a group of Brazilian children. Dental records from 232 patients aged 5–10 years were evaluated by a single trained and calibrated examiner using the diagnostic criteria of the European Academy of Paediatric Dentistry (EAPD). The presence, severity, and clinical characteristics of enamel defects were recorded. Data were analyzed using descriptive statistics, Fisher's exact test, and binomial logistic regression to assess the association between primary canine involvement (exposure) and HSPM (outcome). The prevalence of HSPM was 20.7% (48/232 children) at the patient level and 15.8% (147/928 teeth) at the tooth level, with no significant differences according to sex or age. Among affected children, 68.8% presented mild lesions, whereas 31.2% had at least one severely affected molar. Demarcated opacities were the most common clinical presentation (76.9%). Logistic regression revealed that each additional affected primary canine was associated with a 6.12-fold increase in the odds of HSPM (OR = 6.12; 95%CI: 1.79–20.96; Nagelkerke R2 = 0.145). There was an association between demarcated opacities in primary canines and HSPM. Involvement of primary canines may serve as a clinical marker for the occurrence of HSPM, supporting the implementation of early screening and preventive strategies.

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Cite

BibTeXRIS
BibTeX
@article{ribeiro2026association,
  title = {{Association between demarcated opacities in primary canines and hypomineralized second primary molars}},
  author = {Mylenne Karolayne Silva Ribeiro and Lavínia Lourenço Costa and Luisa Madeira Lemos and Jaderson Felipe Santos Dantas and Patrícia Bittencourt Santos},
  journal = {Brazilian oral research},
  year = {2026},
  month = oct,
  doi = {10.1590/1807-3107bor-2026.vol40.080},
  url = {https://europepmc.org/article/PMC/PMC13711454},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Association between demarcated opacities in primary canines and hypomineralized second primary molars
AU  - Mylenne Karolayne Silva Ribeiro
AU  - Lavínia Lourenço Costa
AU  - Luisa Madeira Lemos
AU  - Jaderson Felipe Santos Dantas
AU  - Patrícia Bittencourt Santos
PY  - 2026
DA  - 2026/10/23
JO  - Brazilian oral research
DO  - 10.1590/1807-3107bor-2026.vol40.080
UR  - https://europepmc.org/article/PMC/PMC13711454
AB  - To evaluate the association between the presence of demarcated opacities in primary canines and the occurrence of hypomineralized second primary molars (HSPM) in a group of Brazilian children. Dental records from 232 patients aged 5–10 years were evaluated by a single trained and calibrated examiner using the diagnostic criteria of the European Academy of Paediatric Dentistry (EAPD). The presence, severity, and clinical characteristics of enamel defects were recorded. Data were analyzed using descriptive statistics, Fisher's exact test, and binomial logistic regression to assess the association between primary canine involvement (exposure) and HSPM (outcome). The prevalence of HSPM was 20.7% (48/232 children) at the patient level and 15.8% (147/928 teeth) at the tooth level, with no significant differences according to sex or age. Among affected children, 68.8% presented mild lesions, whereas 31.2% had at least one severely affected molar. Demarcated opacities were the most common clinical presentation (76.9%). Logistic regression revealed that each additional affected primary canine was associated with a 6.12-fold increase in the odds of HSPM (OR = 6.12; 95%CI: 1.79–20.96; Nagelkerke R2 = 0.145). There was an association between demarcated opacities in primary canines and HSPM. Involvement of primary canines may serve as a clinical marker for the occurrence of HSPM, supporting the implementation of early screening and preventive strategies.
SN  - 1806-8324
SN  - 1807-3107
ER  -