Advancing regenerative biomaterials and translational strategies in orthopaedic traumatology.
7 affiliations
- 1Department of Orthopaedics, University of British Columbia, Vancouver, Canada.
- 2Orthopaedic Trauma Service, Department of Orthopaedic Surgery, Saint Louis University, St. Louis, MO.
- 3Department of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH.
- 4Department of Agricultural and Biological Engineering, Mississippi State University, Mississippi State, MS.
- 5Department of Orthopedic Surgery, University of Texas Health Science Center San Antonio, San Antonio, TX.
- 6Thayer School of Engineering and Geisel School of Medicine, Dartmouth College, Hanover, NH.
- 7Departments of Mechanical and Biomedical Engineering, University of Delaware, Newark, DE.
Abstract
The 2025 Orthopaedic Trauma Association's Basic Science Focus Forum featured a symposium on regenerative biomaterials and translational strategies for orthopaedic trauma. Four experts presented complementary perspectives on the next generation of bone and soft tissue repair: Dr. J. Tracy Watson described how orthobiologics and refined spacer design can be used to engineer a better Masquelet induced membrane; Dr. Lauren Priddy presented evidence that hydroxyapatite coatings can mitigate the rapid degradation of additively manufactured magnesium scaffolds; Dr. Vaida Glatt described the development and clinical translation of the Biomimetic Hematoma scaffold for bone and muscle regeneration; and Dr. Katherine Hixon outlined how the 3R principles (Replacement, Reduction, Refinement) can serve as a framework to accelerate musculoskeletal regenerative engineering. Collectively, the symposium underscored a shift toward biologically informed, clinically predictive, and ethically responsible engineering solutions for the patients who sustain musculoskeletal trauma.
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BibTeX
@article{le2026advancing,
title = {{Advancing regenerative biomaterials and translational strategies in orthopaedic traumatology.}},
author = {Vu Le and J Tracy Watson and Sara McBride-Gagyi and Lauren B Priddy and Vaida Glatt and Katherine R Hixon and Michael W Hast},
journal = {OTA international : the open access journal of orthopaedic trauma},
year = {2026},
month = oct,
doi = {10.1097/oi9.0000000000000509},
url = {https://europepmc.org/article/MED/42953678},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Advancing regenerative biomaterials and translational strategies in orthopaedic traumatology.
AU - Vu Le
AU - J Tracy Watson
AU - Sara McBride-Gagyi
AU - Lauren B Priddy
AU - Vaida Glatt
AU - Katherine R Hixon
AU - Michael W Hast
PY - 2026
DA - 2026/10/23
JO - OTA international : the open access journal of orthopaedic trauma
DO - 10.1097/oi9.0000000000000509
UR - https://europepmc.org/article/MED/42953678
AB - The 2025 Orthopaedic Trauma Association's Basic Science Focus Forum featured a symposium on regenerative biomaterials and translational strategies for orthopaedic trauma. Four experts presented complementary perspectives on the next generation of bone and soft tissue repair: Dr. J. Tracy Watson described how orthobiologics and refined spacer design can be used to engineer a better Masquelet induced membrane; Dr. Lauren Priddy presented evidence that hydroxyapatite coatings can mitigate the rapid degradation of additively manufactured magnesium scaffolds; Dr. Vaida Glatt described the development and clinical translation of the Biomimetic Hematoma scaffold for bone and muscle regeneration; and Dr. Katherine Hixon outlined how the 3R principles (Replacement, Reduction, Refinement) can serve as a framework to accelerate musculoskeletal regenerative engineering. Collectively, the symposium underscored a shift toward biologically informed, clinically predictive, and ethically responsible engineering solutions for the patients who sustain musculoskeletal trauma.
SN - 2574-2167
ER -